Antioxidant, carbonic anhydrase inhibition and diuretic activity of Leptadenia pyrotechnica Forssk. Decne

Masood, Noreena; Jamil, QurratUlAin; Aslam, Muhammad Irfan; Masood, Muhammad Irfan; Shirazi, Jafir Hussain; Jamil, Qazi Adnan; Jan, Muhammad Saeed; Alsuwayt, Bader; Ahmad, Ashfaq; Abdullah Alnasser, Sulaiman Mohammed; Aufy, Mohammed; Iqbal, Shahid Muhammad

doi:10.1016/j.heliyon.2023.e22485

Cited by 4 publications

(1 citation statement)

References 49 publications

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“…Next, 20, 60, and 200 µL of the supernatant were diluted and mixed with FC reagent and sodium carbonate as above-mentioned, and the absorbance was taken. Values were interpolated against the tannic acid calibration curve [78]. The tannin contents were calculated with the following equation Tannins % %total phenolics %non tannin phenolics…”

Section: Quantitative Analysis Of Total Phenols Tannins Flavonoids An...mentioning

confidence: 99%

Pharmacognostic Evaluation, Chemical Characterization, and Antibacterial Activity of Bassia indica (Wight) A.J. Scott

Anjum,

Touqeer,

Khan

et al. 2024

Plants

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Bassia indica (Wight) A.J. Scott is an Indian origin plant with documented medicinal and nutritional value, but has not been fully characterized yet. The present study was designed to establish pharmacognostic standards for the proper identification of the B. indica plant and its chemical characterization. The plant was standardized with World Health Organization (WHO) standardization tools and chemically characterized by Fourier transform infrared spectroscopy (FTIR) and gas chromatography-mass spectroscopy (GC-MS) analysis. Antibacterial potential was assessed by the zone of inhibition and minimum inhibitory concentration (MIC), and molecular docking studies were also performed. Pharmacognostic evaluation established the macroscopic and microscopic parameters for the identification of whole plant and its powder. Physicochemical parameters were also set forth while quantitative phytochemical analysis showed that the ethyl acetate fraction had the highest quantity of phenols, flavonoids, and tannins. FTIR analysis showed several functional groups such as phenols, alkanes, and alcohols while 55 phytochemicals were identified in the GC-MS analysis of the crude fraction. The crude extract and other fractions showed marked antibacterial activity, while the ethyl acetate fraction showed the least MIC (1.95–31.25 mg/mL). Phytochemicals identified in the GC-MS showed good molecular docking interactions against the DNA gyrase subunit B of bacteria with binding energies ranging from −4.2 to −9.4 kcal/mol. The current study describes the pharmacognostic characterization and phytochemical profiling of B. indica and provides scientific evidence to support its use in infections.

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Section: Quantitative Analysis Of Total Phenols Tannins Flavonoids An...mentioning

confidence: 99%

Pharmacognostic Evaluation, Chemical Characterization, and Antibacterial Activity of Bassia indica (Wight) A.J. Scott

Anjum,

Touqeer,

Khan

et al. 2024

Plants

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Dietary supplementation with polyphenol-rich Salicornia ramosissima extracts: Assessing safety, efficacy, and impact on cardiovascular health biomarkers in healthy volunteers

Nájar,

Pérez-Sánchez,

del Río

et al. 2024

Journal of Functional Foods

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Cenchrus ciliaris L. ameliorates cigarette-smoke induced acute lung injury by reducing inflammation and oxidative stress

Aslam,

Touqeer,

Jamil

et al. 2024

South African Journal of Botany

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Antioxidant, carbonic anhydrase inhibition and diuretic activity of Leptadenia pyrotechnica Forssk. Decne

Cited by 4 publications

References 49 publications

Pharmacognostic Evaluation, Chemical Characterization, and Antibacterial Activity of Bassia indica (Wight) A.J. Scott

Pharmacognostic Evaluation, Chemical Characterization, and Antibacterial Activity of Bassia indica (Wight) A.J. Scott

Dietary supplementation with polyphenol-rich Salicornia ramosissima extracts: Assessing safety, efficacy, and impact on cardiovascular health biomarkers in healthy volunteers

Cenchrus ciliaris L. ameliorates cigarette-smoke induced acute lung injury by reducing inflammation and oxidative stress

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