Antioxidant Components of the Flowers of Salvia miltiorrhiza

A new salvianolic acid derivative, (7′E)-(7S, 8S)-salvianolic acid V (1), together with four previously described compounds (2-5) were obtained from the n-butanol fraction of Salvia miltiorrhiza flowers. Their structures were established by a series of spectroscopic methods, and the absolute configuration of 1 was determined by ECD calculation. Salvianolic acids (1) and phenolic acids (2-4) showed stronger DPPH free radical scavenging abilities and certain protective effects against H2O2-induced HSF cells oxidative damage, in which compound 1 (IC50 7.12 μM) possessed more noticeable free radical scavenging activity than the positive control vitamin C (IC50 14.98 μM).

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Antioxidant Components of the Flowers of Salvia miltiorrhiza

Cited by 3 publications

References 8 publications

Chemical Constituents of Phenolic Acids of Salvia miltiorrhiza Flower

Chemical Constituents of Phenolic Acids of Salvia miltiorrhiza Flower

The active ingredient (DSH-20) of Salvia miltiorrhiza flower reduces oxidative damage and apoptosis in cardiomyocytes by regulating miR-1

Isolation and identification of antioxidant constituents from the flowers of Salvia miltiorrhiza

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