Antioxidant, Cytotoxic, and Enzyme Inhibitory Activities of Agropyron repens and Crataegus monogyna Species

Deveci, Ebru; Cayan, Gulsen Tel; Karakurt, Serdar; Duru, Mehmet Emin

doi:10.26650/eurjbiol.2020.0077

Cited by 3 publications

(1 citation statement)

References 32 publications

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“…These properties have appeared to be linked to the presence of phytochemicals generally maintaining the appropriate cell redox balance through diverse mechanisms, including antioxidant activity [ 27 ]. Studies on the genus have shown that phytochemicals such as oligomeric procyanidins, flavonoids, triterpenes, polysaccharides, catecholamines and many of these compounds have been evaluated for biological functions [ 20 , 58 , 59 , 60 ]. In this context, several studies have revealed that the C. monogyna fruit represents a great source and one of the highest in terms of phenolic content with a value up to 30.63 mg gallic acid equivalent (GAE) g −1 in fully ripe fruit [ 61 ].…”

Section: Antioxidant Properties Of Hawthorn Extractsmentioning

confidence: 99%

Botanical, Phytochemical, Anti-Microbial and Pharmaceutical Characteristics of Hawthorn (Crataegus monogyna Jacq.), Rosaceae

et al. 2021

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Hawthorn (Crataegus monogyna Jacq.) is a wild edible fruit tree of the genus Crataegus, one of the most interesting genera of the Rosaceae family. This review is the first to consider, all together, the pharmaceutical, phytochemical, functional and therapeutic properties of C. monogyna based on numerous valuable secondary metabolites, including flavonoids, vitamin C, glycoside, anthocyanin, saponin, tannin and antioxidants. Previous reviews dealt with the properties of all species of the entire genera. We highlight the multi-therapeutic role that C. monogyna extracts could have in the treatment of different chronic and degenerative diseases, mainly focusing on flavonoids. In the first part of this comprehensive review, we describe the main botanical characteristics and summarize the studies which have been performed on the morphological and genetic characterization of the C. monogyna germplasm. In the second part, the key metabolites and their nutritional and pharmaceutical properties are described. This work could be an essential resource for promoting future therapeutic formulations based on this natural and potent bioactive plant extract.

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Section: Antioxidant Properties Of Hawthorn Extractsmentioning

confidence: 99%

Botanical, Phytochemical, Anti-Microbial and Pharmaceutical Characteristics of Hawthorn (Crataegus monogyna Jacq.), Rosaceae

et al. 2021

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Bioactive Content and in vitro Antioxidant and Enzyme-Inhibitory Potential of Leaf and Fruits of Parsnip (Pastinaca sativa L. subsp. Urens)

Eruygur,

Bağcı,

Doğu

et al. 2024

Akademik Gıda

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Parsnip (Pastinaca sativa L. subsp. urens) is one of the species of Pastinaca genus. This plant has been traditionally used worldwide for the treatment of various diseases and cultivated for its nutritional values. The aim of this study was to determine the antimicrobial and enzyme-inhibitory potentials of the fruits and leaves of parsnips as well as their bioactive properties such as their antioxidant activities, total phenolic and flavonoid contents in their hexane and ethanol extracts. The total phenolic and flavonoid contents were determined using Folin-Ciocalteu and aluminum chloride colorimetric methods, respectively. The antioxidant activities of extracts were determined by three methods of DPPH and ABTS radical scavenging activities and iron-chelating ability. In the leaves, the highest total phenolic content (60.94 mg GAE/g extract) was found in ethanol extracts while the highest total flavonoid content (21.47 mg RuE/g extract) was determined in hexane extracts. Ethanol extracts of leaves showed the highest radical scavenging activities in both assays of DPPH and ABTS with the IC50 values of 1039±1.35 and 150.7±0.81 µg/mL, respectively. Growth inhibition zone diameters (mm) of PSFE, PSLE, PSFH, PSLH (2 mg/mL) against reference microorganisms were -/-/15/15, -/-/15/14, 10/10/22/15, -/-/15/14 and MIC values -20>/20>/20>/20>, 20>/20>/20>/2.5, 0.625/10/-/-, 20>/20>/20>/20> mg/mL for Staphylococcus aureus ATCC6538, Micrococcus luteus ATCC9341, Bacillus subtilis ATCC6633, Candida albicans ATCC14053, respectively. Antimicrobial activity was not determined against other reference microorganisms.

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Investigation of in vitro antidiabetic and antioxidant activity of hawthorn vinegar obtained from Endemic Crataegus tanacetifolia (Poir.) Pers.

AKGÜN,

TUĞLU,

AÇIL

et al. 2023

Eurasian Journal of Biological and Chemical Sciences

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In this study, the in vitro antidiabetic, antioxidant activity and total flavonoid content (TFC) and total phenolic content (TPC) of vinegar obtained from endemic Crataegus tanacetifolia (Lam.) Pers. (Rosaceae), (hawthorn) were examined. The hawthorn vinegar obtained from Malatya province (MS) and the vinegar (TS) obtained from Konya were used as study material. Their antidiabetic activity was determined by α-amylase and α-glucosidase inhibitory methods. Antioxidant activities were determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and ferrous iron chelating (FCA) assays. The absorbance were read in the Elisa reader and evaluated with Excel and GraphPad programs. The MS has been found to have higher α- amylase (95.12± 3.71%) and α-glucosidase inhibitory (81.62 ± 0.33%) effects. The TS demonstrated (94.13 ± 3.85%) α-amylase and (75.35 ± 2.19%) α-glucosidase inhibitory activity, respectively. The TPC was found to be in TS (467.59 ± 6.73) mg GAE/mL MS (328.46 ± 5.50) mg GAE/mL. The TFC was found as (1.94 ± 10.36) mg CE/mL and (1.32 ± 10.96) mg CE/mL in TS and MS vinegar, respectively. The FCA was found to be in TS (33.37 ± 0.53%) MS (31.08 ± 10.87%). The DPPH radical scavenging activity was found as (73.82 ± 2.12%) in TS and (80.12 ± 4.45%) in MS. ABTS radical scavenging activity was found to be the highest in TS with (82.51± 0.78%) and in MS found as (78.65 ± 0.55%). The antidiabetic, antioxidant activity, TPC and TFC determinations of these vinegars were performed for the first time with these methods.

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Antioxidant, Cytotoxic, and Enzyme Inhibitory Activities of Agropyron repens and Crataegus monogyna Species

Cited by 3 publications

References 32 publications

Botanical, Phytochemical, Anti-Microbial and Pharmaceutical Characteristics of Hawthorn (Crataegus monogyna Jacq.), Rosaceae

Botanical, Phytochemical, Anti-Microbial and Pharmaceutical Characteristics of Hawthorn (Crataegus monogyna Jacq.), Rosaceae

Bioactive Content and in vitro Antioxidant and Enzyme-Inhibitory Potential of Leaf and Fruits of Parsnip (Pastinaca sativa L. subsp. Urens)

Investigation of in vitro antidiabetic and antioxidant activity of hawthorn vinegar obtained from Endemic Crataegus tanacetifolia (Poir.) Pers.

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