Antioxidant defense in the hibernating thirteen-lined ground squirrel Spermophilus tridecemlineatus

Transcriptional regulation in the hibernating thirteen-lined ground squirrel, Spermophilus tridecemlineatus

“…A recent study has shown that the enzyme contains multiple AREs in its promoter region (Ellis et al, 2003). Preliminary work in our lab (Ni, 2004) has also shown that Nrf2 and HO-1 were elevated in tissue samples from ground squirrels that had been hibernating for more than 3 days.…”