Antioxidant Effect of Cocoa By-Product and Cherry Polyphenol Extracts: A Comparative Study

Felice, Francesca; Fabiano, Angela; Leo, Marinella De; Piras, Anna Maria; Beconcini, Denise; Cesare, Maria Michela; Braca, Alessandra; Zambito, Ylenia; Stefano, Rossella Di

doi:10.3390/antiox9020132

Cited by 21 publications

(26 citation statements)

References 44 publications

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“…Elutions were performed at a flow rate of 0.8 mL/min with a splitting system of 2:8 to MS detector (160 μL/min) and PDA detector (640 μL/min), respectively [ 53 ]. The volume of the injected methanol solutions was 20 μL.…”

Section: Methodsmentioning

confidence: 99%

Flaxseed and Camelina Meals as Potential Sources of Health-Beneficial Compounds

Tavarini

Leo

Matteo³

et al. 2021

Plants

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Seed meals and cakes, deriving from minor oilseed crops, represent interesting co-products for the presence of a high content of proteins and bioactive compounds that could be successfully explored as valuable plant-derived feedstocks for food and non-food purposes. In this contest, flaxseed (Linum usitatissimum L.) and camelina (Camelina sativa (L.) Crantz) are becoming increasingly important in the health food market as functional foods and cosmetic ingredients. Thus, this study aimed to evaluate the effect of genetic characteristics and cultivation sites on the chemical features of seed meals deriving from two flaxseed varieties (Sideral and Buenos Aires) and a camelina cultivar (Italia), cultivated in Central and Northern Italy (Pisa and Bologna). The content of total phenols and flavonoids, seed oil, proteins and fatty acids have been evaluated, together with the chemical profiles of flaxseed and camelina meals. In addition, radical-scavenging activity has been investigated. All the examined seed meals resulted as rich in bioactive compounds. In particular, flaxseed meal is a good source of the lignan secoisolariciresinol diglucoside (SDG) and hydroxycinnamic acid glucosides, while camelina meal contains glucosinolates and quercetin glycosides. Furthermore, all extracts exhibited a very strong radical-scavenging activity, that make these plant-derived products interesting sources for food or cosmetic ingredients with health outcomes.

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Section: Methodsmentioning

confidence: 99%

Flaxseed and Camelina Meals as Potential Sources of Health-Beneficial Compounds

Tavarini

Leo

Matteo³

et al. 2021

Plants

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“…These properties are largely linked to the antioxidant properties attributed to the bioactive phytochemicals contained in the cocoa fruit [ 3 ]. In cocoa beans, phenolic compounds represent about 10% of total constituents [ 8 ] and they are mainly made up of proanthocyanidins (58%), flavonols or flavan-3-ols (37%) and anthocyanins (4%) [ 9 ]. These secondary metabolites are of great interest since they possess high antioxidant activity with applicability in the food industry.…”

Section: Introductionmentioning

confidence: 99%

LC-MS and Spectrophotometric Approaches for Evaluation of Bioactive Compounds from Peru Cocoa By-Products for Commercial Applications

et al. 2020

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Peru is one of the main areas where there are large cocoa crops with special relevance to the economy of this country. In fact, cocoa is a major, economically important, international crop which has been linked to several benefits, such as anti-allergenic, anti-atherogenic, anti-inflammatory, anti-microbial, anti-oxidant, anti-thrombotic, cardioprotective and vasodilatory properties, relating to its bioactive compound content. However, in cocoa industrial processing, several residues or wastes, which are commonly discarded generating a negative impact on the environment, are produced in large amounts. Some of the cocoa by-products, which go underutilized, could be a good source of bioactive compounds with high utility for the development of innovative products in nutraceutical, medical or pharmaceutical industries. For this reason, the aim of this study is to qualitatively determine the phytochemical composition of husk and bean extracts from different cocoa-growing areas and processes from Peru by high performance liquid chromatography coupled to mass spectrometry. Furthermore, we aim to evaluate their phenolic and flavan-3-ol contents and antioxidant capacities for the purpose of highlighting the potential of cocoa by-products from these cultivars as functional ingredients. In total, 49 chemical compounds were detected in the analyzed extracts. Comparing both husks and beans, bean extracts were characterized by high content in flavonoids whereas husk extracts had a higher content of phenolic acids. The presence of these compounds together with the bioactivity results suggest that these matrices may be further studied for their revaluation in the development of high added-value products in nutraceutical, medical, and pharmaceutical industries.

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“…Many agri-food extracts are important sources of polyphenols, that is, molecules of high interest thanks to an ample variety of biological activities [119]. However, a low bioavailability is the major problem of using antioxidants from agri-food extracts in the therapy.…”

Section: No-[nn-diethylaminomethyl(diethyldimethylene Ammonium)nmetmentioning

confidence: 99%

Quaternary Ammonium Chitosans: The Importance of the Positive Fixed Charge of the Drug Delivery Systems

Fabiano

Beconcini

Migone

et al. 2020

IJMS

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As a natural polysaccharide, chitosan has good biocompatibility, biodegradability and biosecurity. The hydroxyl and amino groups present in its structure make it an extremely versatile and chemically modifiable material. In recent years, various synthetic strategies have been used to modify chitosan, mainly to solve the problem of its insolubility in neutral physiological fluids. Thus, derivatives with negative or positive fixed charge were synthesized and used to prepare innovative drug delivery systems. Positively charged conjugates showed improved properties compared to unmodified chitosan. In this review the main quaternary ammonium derivatives of chitosan will be considered, their preparation and their applications will be described to evaluate the impact of the positive fixed charge on the improvement of the properties of the drug delivery systems based on these polymers. Furthermore, the performances of the proposed systems resulting from in vitro and ex vivo experiments will be taken into consideration, with particular attention to cytotoxicity of systems, and their ability to promote drug absorption.

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Antioxidant Effect of Cocoa By-Product and Cherry Polyphenol Extracts: A Comparative Study

Cited by 21 publications

References 44 publications

Flaxseed and Camelina Meals as Potential Sources of Health-Beneficial Compounds

Flaxseed and Camelina Meals as Potential Sources of Health-Beneficial Compounds

LC-MS and Spectrophotometric Approaches for Evaluation of Bioactive Compounds from Peru Cocoa By-Products for Commercial Applications

Quaternary Ammonium Chitosans: The Importance of the Positive Fixed Charge of the Drug Delivery Systems

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