Antioxidant effect of organic purple grape juice on exhaustive exercise

Corte, Cristiane Lenz Dalla; Carvalho, Nélson Rodrigues de; Amaral, Guilherme Pires; Puntel, Gustavo Orione; Silva, Luiz Fernando A.; Retamoso, Leandro Thies; Royes, Luiz Fernando Freire; Bresciani, Guilherme; Cruz, Ivana Beatrice Mânica da; Rocha, João Batista Teixeira da; Lera, Juan Pablo Barrio; Soares, Félix Alexandre Antunes

doi:10.1139/apnm-2012-0230

Cited by 23 publications

(18 citation statements)

References 38 publications

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“… Huang et al (2013) reported that physical exercise induced oxidative stress which could cause damage to muscle and liver tissues ( Huang et al, 2013 ). Dalla Corte et al (2013) demonstrated that elevation of oxidative damage markers in the brain, skeletal muscle, and blood after exhaustive exercise ( Dalla Corte et al, 2013 ). The results of all these studies investigating effects of exercise in the literature demonstrated is conflicted.…”

Section: Discussionmentioning

confidence: 99%

Effect of acute and chronic exercise on plasma matrix metalloproteinase and total antioxidant levels

Tunç-Ata¹,

Mergen-Dalyanoglu²,

Turgut³

et al. 2017

J Exerc Rehabil

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The relationship between acute and chronic exercise and expression of matrix metalloproteinases (MMPs) in muscles is unknown. There happen some alterations in the oxidant-antioxidant balance due to exercise. This study aimed to investigate the levels of MMP-1, tissue inhibitors of metalloproteinases (TIMP-1), hyaluronic acid (HA), total antioxidant status (TAS), and total oxidant status (TOS) following acute and chronic exercising in rats. Twenty-six Wistar Albino male rats were divided in to three groups: control, acute, and chronic groups. In acute group, treadmill exercise was performed 3 days/wk, 10 min/day for 1 week. In chronic group, exercise performed 7 days/wk, 60 min/day for 4 weeks. At the end of the experiment, plasma MMP-1, TIMP-1, HA, TAS, and TOS levels were measured. In current study, the MMP-1, TIMP-1, HA, and TOS levels not observed statistically significant difference among all groups, but in chronic group, there was a significantly difference (P<0.05) between the control and experimental groups in terms of TAS and oxidative stress index (OSI) levels. TAS, TOS, and OSI levels were significantly different between control and chronic exercise group (P<0.01, P<0.05, and P<0.01, respectively). According to these results, we can say acute and chronic exercise does not effect on plasma MMP-1, TIMP-1, and HA levels.

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Section: Discussionmentioning

confidence: 99%

Effect of acute and chronic exercise on plasma matrix metalloproteinase and total antioxidant levels

Tunç-Ata¹,

Mergen-Dalyanoglu²,

Turgut³

et al. 2017

J Exerc Rehabil

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“…Studies on laboratory animals have suggested that acute aerobic exercise increases oxidative stress levels not only in blood but also in tissues such as skeletal muscle and the brain, heart, lungs, liver, kidneys, and spleen [ 54 , 55 , 56 , 57 , 58 , 59 ]. It must be noted that, as Liu et al, demonstrated in 2000, the oxidative stress response to acute aerobic exercise is tissue specific [ 60 ].…”

Section: Exercise-induced Oxidative Stressmentioning

confidence: 99%

Exercise-Induced Oxidative Stress and the Effects of Antioxidant Intake from a Physiological Viewpoint

2018

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It is well established that the increase in reactive oxygen species (ROS) and free radicals production during exercise has both positive and negative physiological effects. Among them, the present review focuses on oxidative stress caused by acute exercise, mainly on evidence in healthy individuals. This review also summarizes findings on the determinants of exercise-induced oxidative stress and sources of free radical production. Moreover, we outline the effects of antioxidant supplementation on exercise-induced oxidative stress, which have been studied extensively. Finally, the following review briefly summarizes future tasks in the field of redox biology of exercise. In principle, this review covers findings for the whole body, and describes human trials and animal experiments separately.

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“…On the other hand, under HIE training, ROS production may be strongly and persistently increased, and the antioxidant response may not be effective to reset the system to the original levels of brain redox homeostasis [3]. In fact, HIE has been shown to induce oxidative stress and increase lipid peroxidation in a mouse brain [18,53]. In view of these contradictory results in the literature, our findings agree with some of the aforementioned studies in that no significant evidence was observed in brain TBARs levels after an HIE protocol.…”

Section: High-intensity Exercise Anabolic Androgenic Steroids and Brmentioning

confidence: 99%

High-intensity Exercise Modifies the Effects of Stanozolol on Brain Oxidative Stress in Rats

et al. 2015

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We analyzed the effects of high-intensity exercise (HIE) and anabolic androgenic steroids (AAS) on brain redox status. 40 male Wistar rats were randomly distributed in 4 experimental groups (n=10) with or without HIE and with or without weekly Stanozolol administration. Thiobarbituric acid-reactive substances (TBARs) and protein carbonyl content (PCC) were assessed. Total superoxide dismutase (tSOD), manganese superoxide dismutase (Mn-SOD), copper/zinc superoxide dismutase (CuZn-SOD) and catalase (CAT) activities were measured. Finally, protein expression levels of glutathione peroxidase (GPx), NAD(P)H dehydrogenase, Quinone 1 (NQO1), NF-E2-Related Factor 2 (Nrf2), glial fibrillary acidic protein (GFAP), nuclear factor kappa β p65 (NF-κβ) and signal transducer and activator of transcription 3 were determined. Brain PCC concentrations were lower in the HIE groups compared to the untrained controls, whereas CAT activity was higher (both, p<0.01). Both HIE and AAS groups exhibited higher expression levels of GFAP and GPx, but lower NQO1 levels (all, p<0.05). There were increased expression levels of NF-κβ in the AAS groups (p<0.01). In addition, there was increased expression of Nrf2 in the HIE groups (p<0.001). HIE*AAS interactions were found on TBARs content and GFAP expression, with HIE downregulating and upregulating AAS-mediated increases in TBARs and GFAP, respectively (p<0.05). Overall, HIE appeared to reduce the AAS-mediated negative effect on brain redox status.

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Antioxidant effect of organic purple grape juice on exhaustive exercise

Cited by 23 publications

References 38 publications

Effect of acute and chronic exercise on plasma matrix metalloproteinase and total antioxidant levels

Effect of acute and chronic exercise on plasma matrix metalloproteinase and total antioxidant levels

Exercise-Induced Oxidative Stress and the Effects of Antioxidant Intake from a Physiological Viewpoint

High-intensity Exercise Modifies the Effects of Stanozolol on Brain Oxidative Stress in Rats

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