Antioxidant effects and cytotoxicity of three purified polysaccharides from Ligusticum chuanxiong Hort.

Essential oil from rhizomes ofLigusticum chuanxionginduces apoptosis in hypertrophic scar fibroblasts

“…Ethyl ether extract of RCX blocks endothelial cell damage induced by hydrogen peroxide (Hou et al, 2004). The polysaccharides from RCX also have antioxidant effects and cytotoxicity in human liver carcinoma cell line (Yuan et al, 2008). Until now, to the best of our knowledge, there have been no reports on induction of apoptosis by EO from the rhizomes of Ligusticum chuanxiong in hypertrophic scar fibroblasts (HSFs).…”

Structural characterization and biological activities of a novel polysaccharide from <i>Phyllanthus emblica </i>

“…Hydroxyl radical can easily cross cell membranes, readily react with most biomolecules including carbohydrates, proteins, lipids, and DNA in cells, and cause tissue damage or cell death (41). The IC 50 value of PEPW80-1 was 2.0 mg/mL, which was less than the polysaccharide from Panax japonicus (5 mg/mL) (40).…”

Antidiabetic mechanism ofCoptis chinensispolysaccharide through its antioxidant property involving the JNK pathway

“…Polysaccharide offers many biological effects such as structural support, protective function, and energy storage. A plethora of experimental results have shown that polysaccharides possess the properties of immunoregulation, anticancer, antioxidation, antifatigue, and lowering blood sugar, cholesterol, and blood lipid (Chen & Qi, 2013;Chen et al, 2008;Jiang et al, 2008;Yuan et al, 2008). It is a popular topic in the medical field around the world due to its low toxicity, fewer side effects and high impact on the body (Arumugam et al, 2008;Chi et al, 2008).…”