Antioxidant-oxidant status in patients with hydatid cyst

Bakır, Sevtap; Çeliksöz, Ali; Çelık, Veysel Kenan; Sarı, İsmail; Aydın, Hüseyin

doi:10.5505/tjb.2012.54154

Cited by 5 publications

(3 citation statements)

References 27 publications

(28 reference statements)

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“…Oxida ve stress can be measured by calcula ng the ra o of total oxidant status (TOS) and total an oxidant status (TAS). 10,22 In the present study there was a highly signifi cant increase in the total oxidant status in leprosy pa ents in comparison to healthy controls (P<0.0001) and there was a highly signifi cant decrease in mean total an oxidant status in leprosy in comparison to healthy controls (P<0.0001). This supports the theory that genera on of free radicals are involved in the pathogenesis of leprosy.…”

Section: Discussionsupporting

confidence: 50%

Enzymatic Oxidative Stress Indicators and Oxidative Stress Index in Patients of Leprosy

Raka

Rastogi

Gahalaut

et al. 2018

Nepal J Dermatol Venereol & Leprol

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Introduction: Leprosy is a chronic granulomatous disease caused by Mycobacterium leprae. Oxidative stress caused by Reactive oxygen species (ROS) plays a crucial role in the pathogenesisis of leprosy.Objective: To measure the enzymatic oxidative stress indicators and oxidative stress index in patients of leprosy and compare them with healthy age & sex matched controls.Materials and Methods: In this prospective study 30 untreated leprosy patients were included in the study and matched with 60 healthy controls. Biochemistry estimation was done with blood samples and MDA (lipid peroxidation), Nitric oxide (NO), (SOD) Superoxide dismutase (antioxidant enzyme), total oxidant status (TOS), total antioxidant status(TAS) and oxidative stress index (OSI) were estimated.Results: Highly significant rise (p<0.0001) in serum MDA, NO, TOS and OSI was seen in leprosy patients when compared with controls with highly significant decline in SOD and TAS.Conclusion: The study confirms the oxidative stress in leprosy and suggests antioxidant therapy may be used as an adjuvant in the treatment of leprosy along with MDT.

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Section: Discussionsupporting

confidence: 50%

Enzymatic Oxidative Stress Indicators and Oxidative Stress Index in Patients of Leprosy

Raka

Rastogi

Gahalaut

et al. 2018

Nepal J Dermatol Venereol & Leprol

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“…Bakır et al, 21 reported that oxidative stress increased in patients with hydatid cyst. In the same study, serum total antioxidant status, total oxidant status levels and oxidative stress index levels were found to be significantly higher in hydatid cyst patients compared to control, whereas paraoxonase and arylesterase activities were significantly lower in hydatid cyst patients compared to control.…”

Section: Resultsmentioning

confidence: 99%

Determination of Oxidant / Antioxidant Levels in Sheep with Hydatite Cyst in Liver

Mahmood¹,

Mert²,

Mert³

2020

IJFMT

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The larval form of Echinococcus granulosus, hydatid cyst is an important parasitic zoonosis commonly seen in animals and humans. The aim of this study was to investigate the efficacy of oxidative stress on the pathogenesis of cystic echinococcosis with antioxidant / oxidant status in sheep sera. The material of the study was composed of sheep infected with hydatid cyst and healthy cut in slaughterhouse in Van province. The general health status of the sheep before slaughtering was checked by physical examination and blood samples were taken. After slaughtering, cyst hydatid examination was performed in different organs of the animals. The control group consisted of 25 sheep study cases with positive (fertil cyst) and 15 sheep without any pathological lesion on organ examinations and healthy on physical examination. Blood samples taken from animals infected with healthy and hydatid cysts were transported to the laboratory under appropriate conditions and centrifuged. Total antioxidant / oxidant status, paraoxonase and arylesterase activities were measured by using commercial kits. Compared with cystic echinococcosis group and healthy group, the importance was calculated on the TAS, PON1 activities (P <0.01), TOS, ARES activities differences (P <0.001), It decreases. This may cause tissue necrosis and increased inflammation . Decrease in antioxidant reserves; excessive free radical formation in the ewes with cystic echinococcosis causes deterioration of the normal histological structure of the organ in the cyst.

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“…The final host is carnivores, and intermediate hosts include camels, sheep, goats, cattle, small rodent, wild herbivores and humans. This parasite might inhabit especially in liver and lung than other organs (e.g., kidneys, spleen, brain, bones, and heart) (Bakır et al, 2012). Hydatidosis is an economically important disease as it causes severe problems in different species animals especially in the industrial and semi-industrial cattle farms by close contact with the final host via domestic and wildlife reservoirs (Umesh et al, 2010).…”

Section: -Introductionmentioning

confidence: 99%

Occurance of hydratic cyst in camels (Camelus dromedarius) and their effect on meat quality

2016

Egyptian Journal of Chemistry and Environmental Health

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Hydatidosis is caused by Echinococcus granulosus which is one of the important parasitic disease in warm blooded vertebrates and occasionally in many other mammal species. Their were no enough informations available regarding haematological profile, serum enzyme activity, chemical changes, and mineral profile in one humped camels (Camelus dromedaries) from Egypt with pulmonary hydatid cyst. The objective of the present study was to investigate the changes in complete haematological profile and also changes in some biochemical parameters in serum samples, such as; Total Protein, Albumin, Globulin, A/G ratio, serum liver enzyme activity such as; Alanine Amino Transaminase (ALT), Aspartate Amino Transferase (AST), bilirubin, glucose, cholesterol, also, kidney function activity as; Urea, Uric acid, and Creatinine, also, the level of complete Minirals profile, such as; Calcium, Inorganic phosphorus, Magnesium, Sodium, and Potassium were also done. Meat chemical composition of healthy and infected camels with Echinicoccus granulosus, was also made as nutrition value, proteins, fats, ashes, mineral elements, as, calcium level in meat samples was measured and compared to samples from healthy camels at abattoir, a total of Fifty samples of meat, serum and hydatid cysts from lungs were collected from camels admitted to slaughter houses at Qalyubia Governorate, Egypt. Results concluding that; meat from the camel infected with echinococcosis is of poorer quality as compared with muscle tissue of the healthy animal as well as being biologically inferior, there were a significant increase in leucocytic count, neutrophils and eosinophils while the other haemograms are non significant. More over significant increase in total protein, and globulin in sera of infected camel with hydatidosis when compared with the non infected ones. Decreased in A/G ratio reflected the changes observed in albumin and globulin fractions. A significant elevation of the activity of AST, ALT and bilirubin level (p<0.05), but a significant decrease in glucose value, and there is no alteration in serum cholesterol, urea, uric acid and creatinine level was observed. Concerning calcium and inorganic phosphorus levels, they were significant decrease, and this study showed non-

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Antioxidant-oxidant status in patients with hydatid cyst

Cited by 5 publications

References 27 publications

Enzymatic Oxidative Stress Indicators and Oxidative Stress Index in Patients of Leprosy

Enzymatic Oxidative Stress Indicators and Oxidative Stress Index in Patients of Leprosy

Determination of Oxidant / Antioxidant Levels in Sheep with Hydatite Cyst in Liver

Occurance of hydratic cyst in camels (Camelus dromedarius) and their effect on meat quality

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