Antioxidant Potential and Modulatory Effects of Amazonian Restructured Lipids in Liver Cells

Falcão, Andrea de Oliveira; Speranza, Paula; Ueta, Tatiane Mayumi; Martins, Isabela Mateus; Macedo, Gabriela Alves; Macedo, Juliana Alves

doi:10.17113/ftb.55.04.17.5157

Cited by 6 publications

(5 citation statements)

References 19 publications

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“…In a previous study carried out by our research group, the antioxidant capacity was also higher of the structured lipids produced with Lipozyme TL-IM and enzyme from Rhizopus sp., respectively, followed by pure buriti oil. This result indicates that enzymatic interesterification significantly increased the antioxidant capacity of the oil, independently of the content of minor compounds ( 55 ). In a study by Poyato et al ( 56 ), the antioxidant capacity expressed as Trolox equivalents, measured by the L-ORAC (lipophilic radical absorption capacity of oxygen) assay, of linseed oil emulsions (8315.4 μmol/100 g) was higher than those of NLCs developed in the present study, whereas for olive oil emulsions (1978.9 μmol/100 g) was similar to those of NLCs.…”

Section: Resultsmentioning

confidence: 80%

Evaluation of Nanostructured Lipid Carriers Produced with Interesterified Buriti Oil

Reis

Leão

Speranza

et al. 2020

Food Technol. Biotechnol. (Online)

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Research background. Extracted from the pulp of an Amazonian fruit, buriti oil is rich in micronutrients with antioxidant properties and has high biological value. The few studies available indicate that this oil could be used in a wide range of applications; however, there are no studies that work on the improvement in the characteristics of this oilfor commercial application. The enzymatic interesterification is one of the tools available to improve the properties of oils and fats and our recent studies demonstrated that the lipase could specifically act on buriti oil to produce structured lipids rich in oleic acid, while preserving most of minority compounds present in this oil. Still looking for ways to expand applicability of this raw oil, in this recent work, we are interested in studying how is the behavior of this structured oil in nanostructured lipid carriers (NLCs). Experimental approach. Samples were stored at 4 and 25 °C for 30 days and their physicochemical properties were evaluated. Results and conclusions. The results showed that the interesterification formed more unsaturated triacylglycerols (TAGs) and NLCs prepared with interesterified buriti oil presented small droplets than NLCs with original buriti oil. Particles remained stable throughout the storage period and NLCs exhibited complex polymorphism with the presence of three crystalline forms. The ORAC value was approximately 23 % higher in nanolipid carries with structured lipids in comparison with the nano lipid carriers with original buriti oil, and the FRAP value, 16 % higher, demonstrating the influence of interesterification on the antioxidant activity of nanocarriers. Thus, NLCs prepared with interesterified buriti oil exhibit smaller droplets, high stability and antioxidant capacity and have potential for nutritional and biological applications. Novelty and scientific contribution. This research showed that interesterification positively influenced the physicochemical properties of NLCs, producing oils rich in oleic acid, high stability and antioxidant capacity. Therefore, it may be interesting to use these nanocarriers to obtain efficient carrier systems for future applications.

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Section: Resultsmentioning

confidence: 80%

Evaluation of Nanostructured Lipid Carriers Produced with Interesterified Buriti Oil

Reis

Leão

Speranza

et al. 2020

Food Technol. Biotechnol. (Online)

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“…A. vulgare fruits have also been standing out as an important source of carotenoids due to its high number of total carotenoids identified in the edible part of the fruit (122.23 ± 3.45 mg/100g oil) which is greater than the amount identified in the A. aculeatum mesocarp (6.265 mg/100g oil) and in the fat of the A. murumuru seed (2.18 ± 0.16 mg/100g oil) (ABREU et al, 2020;SANTOS et al, 2015;FALCÃO et al, 2017).…”

Section: Phenolic Compounds and Carotenoid Compositionmentioning

confidence: 99%

Tucumã of Pará oil: chemical profile, biological activities, and methods of extraction

Mendonça Morais,

Roberta Pinheiro Pantoja,

Gama Ortiz Menezes

et al. 2023

PRW

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The present work research involves a systematic review of the chemical profile and biological activities of vegetable oil from the Astrocaryum species identified in Brazilian amazon rainforest. Astrocaryum consists of a important group of botanical species that have economic value in the national and international fruit market. Furthermore, the species has application in several areas such as pharmacology, biotechnology, and medicine. In folk medicine, species such as Astrocaryum aculeatum M. and Astrocaryum vulgare M. are used in prevention of diabetes and inflammatory diseases. The species of Astrocaryum are natural source of vegetable oil and are rich in bioactive compounds belonging to the classes of carotenoids, of these compounds β-carotene is the most abundant. The cytoprotective, anti-inflammatory and antimicrobial activities of vegetable oils from the Astrocaryum species in Brazilian amazon rainforest have been described in previous research.

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“…For many such species, the fruits and associated lipids are already traditionally used in many aspects of the local communities' lives, including as food and medicine, and can form part of their cultural and economic fabric [8,9]. Most of the oleaginous plants that thrive in these environments [7] are of particular interest, as their lipids often possess distinctive physical, chemical and bioactive properties, making them of potential interest in varied high-value foods, pharmaceuticals and cosmetics [7,10,11]. Although research in the area is increasing, these materials are generally not thoroughly or at all studied by mainstream academia.…”

Section: Introductionmentioning

confidence: 99%

“…Other fatty acids found in AVP include α-linolenic (C18:3), linoleic (C18:2) and stearic (C18:0) acids [22,28,29]. The oil from AAP has a similar fatty acid profile, with up to 74% UFAs that are also dominated by oleic acid (47-64%) and palmitic acid as the dominant fatty acid (10)(11)(12)(13)(14) [30,31]. AVK and AAK oils are highly saturated, with lauric acid (C12:0) and myristic acid (C14:0) dominating in both.…”

Section: Introductionmentioning

confidence: 99%

Molecular, Crystalline, and Microstructures of Lipids from Astrocaryum Species in Guyana and Their Thermal and Flow Behavior

Deonarine,

Soodoo,

Bouzidi

et al. 2024

Thermo

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The phase behavior of lipids extracted from Astrocaryum vulgare (AV) and Astrocaryum aculeatum (AA) pulp and kernels and their microstructural, thermal and flow properties were studied. The lipid profiles, crystal structures, microstructures, thermal stabilities and flow behaviors of these lipids provided important structure–function information that are useful to assess potential applications in the food, cosmetic and pharmaceutical industries. AV and AA fruits were sourced from the lowlands and rainforests, respectively, of Guyana. AV and AA pulp oils (AVP and AAP) were distinguished from each other in composition and unsaturation, with AVP oils being predominated by a di-unsaturated TAG (2-(palmitoyloxy)propane-1,3-diyl dioleate (POO)) and AAP oils predominated by propane-1,2,3-triyl trioleate (OOO); there were unsaturation levels of 65% and 80%, respectively. The main fatty acids in AVP oils were oleic, palmitic and stearic; for AAP, these were oleic, linoleic, palmitic and stearic. The kernel fats of AV and AA were similar in composition and had saturation levels of 80%, being mainly comprised of tri-saturated TAGs propane-1,2,3-triyl tridodecanoate (LLL) and 3-(tetradecanoyloxy)propane-1,2-diyl didodecanoate (LML). The onset of mass loss (T5%on) of AV and AA pulp oils were similar at 328 ± 6 °C, which were 31 °C ± 9 higher compared to that of the kernel fats, which demonstrated similar T5%on = 293 ± 7 °C. AA and AV pulp oils were liquid at room temperature, with melting points of −5 ± 1 °C and 3 ± 1 °C, respectively; both kernel fats were solid at room temperature, packing in β′ (90% of crystals) and β (10% of crystals) polymorphic forms and melting almost identically at 30 ± 1 °C. Pulp oils demonstrated sporadic nucleation at the onset of crystallization with slow growth into rod-shaped crystallites, leading to an approximately 50% degree of crystallization at undercooling of approximately 40K. Nucleation for kernel fats was instantaneous at undercooling of approximately 23K, demonstrating a spherulitic growth pattern incorporating crystalline lamella and a 90% degree of crystallization. Kernel fats and pulp oils demonstrated Newtonian flow behavior and similar dynamic viscosity in the melt, approximately 28.5 mPa·s at 40 °C. The lipid profiles of AVP and AAP oils were dominated by unsaturated TAGs, suggesting potential nutrition and health benefits, particularly compared to other tropical oils with higher saturation levels, such as palm oil. AAP oil in particular is as unsaturated as olive oil, contains high levels of beta carotene and provides a unique flavor profile. The AAK and AVK lipid profiles and phase transformation indicate potential for applications where a high solid fat content and medium-chain fatty acids are required. Their high lauric and myristic acid content makes them similar to industrially important tropical oils (coconut and palm kernel), suggesting their use in similar formulations. The melting point and plasticity of the kernel fats are similar to that of cocoa and shea butters, suggesting use as replacements in cosmetics, foods and confections. There is, however, the need to better understand their nutritional status and effects on health.

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Antioxidant Potential and Modulatory Effects of Amazonian Restructured Lipids in Liver Cells

Cited by 6 publications

References 19 publications

Evaluation of Nanostructured Lipid Carriers Produced with Interesterified Buriti Oil

Evaluation of Nanostructured Lipid Carriers Produced with Interesterified Buriti Oil

Tucumã of Pará oil: chemical profile, biological activities, and methods of extraction

Molecular, Crystalline, and Microstructures of Lipids from Astrocaryum Species in Guyana and Their Thermal and Flow Behavior

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