Antioxidant Potential of Cordia dichotoma: A Review

Dhakar, Ram Chand; Prajapati, Sunil Kumar; Maurya, Sandip; Tilak, Vijay Kumar; Das, Manas Kumar; Das, Soumya; Jain, Nilesh

doi:10.22270/ajdhs.v1i1.6

Cited by 4 publications

(1 citation statement)

References 14 publications

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“…Phenolic constituents in the extract have the ability to interact with transition metals by filling their aqua coordination sites. 55 This interaction can result in the generation of metal coordinates and insoluble complexes, contributing to antioxidant effects. Phenolic compounds, such as flavonoids, are known for their chelation properties, forming stable complexes with metal ions.…”

Section: Antileishmanial Activitymentioning

confidence: 99%

Exploring the Therapeutic Potential: Phytochemistry and Pharmacology of Bryophyllum pinnatum

Dhumane,

Naik,

Shelke

et al. 2024

J. Drug Delivery Ther.

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Bryophyllum pinnatum, a renowned medicinal plant with a rich history in various traditional medical practices, has been utilized for treating a range of ailments such as fever, smallpox, otitis, cough, asthma, headache, convulsion, and general debility. The plant's diverse secondary metabolites, including steroids, flavonoids, terpenoids, fatty acids, bufadienolides, proteins, peptides, vitamins, and polysaccharides, have been identified. Over the past thirty years, extensive research has unveiled the plant's pharmacological effects both in vivo and in vitro, demonstrating its antimicrobial, anti-ulcer, antihypertensive, antileishmanial, anti-cancer, antidiabetic, and immunomodulatory properties. This comprehensive review aims to provide a consolidated overview of Bryophyllum pinnatum, encompassing its traditional uses, phytochemistry, and pharmacological studies. By presenting a wealth of information, this paper seeks to inspire further exploration into the potential beneficial applications of the plant. Additionally, it sheds light on the clinical uses and prospects of Bryophyllum pinnatum, offering valuable insights for future research endeavors. Keywords: Bryophyllum pinnatum, Chemical Constituent, Biological activities, antioxidant effect, Therapeutic potential

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Section: Antileishmanial Activitymentioning

confidence: 99%

Exploring the Therapeutic Potential: Phytochemistry and Pharmacology of Bryophyllum pinnatum

Dhumane,

Naik,

Shelke

et al. 2024

J. Drug Delivery Ther.

View full text Add to dashboard Cite

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Antioxidants and the Prevention of Congenital Heart Defects

Obeagu,

Obeagu

2024

Int J Med Sci Pharm Res

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Congenital heart defects (CHDs) are among the most prevalent congenital anomalies, contributing significantly to neonatal morbidity and mortality. Emerging evidence indicates that oxidative stress is a key factor in the etiology of CHDs, as increased levels of reactive oxygen species (ROS) during critical periods of fetal development can lead to cellular damage and impaired cardiac morphogenesis. This narrative review explores the mechanisms by which oxidative stress contributes to the development of congenital heart defects and highlights the role of antioxidants in mitigating these effects. Antioxidants, including vitamins C and E, selenium, and coenzyme Q10, have demonstrated potential in reducing oxidative damage and supporting maternal and fetal health. Their ability to neutralize ROS can help protect developing cardiac tissues from oxidative injury, thereby promoting normal cardiac development. This review examines current research on the impact of antioxidant supplementation on pregnancy outcomes and its implications for preventing congenital heart defects. Keywords: Antioxidants, congenital heart defects, oxidative stress, maternal health, prenatal nutrition

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Oxidative Stress and Pregnancy-induced Hypertension: Antioxidant Solutions

Obeagu

2024

Int J Med Sci Pharm Res

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Pregnancy-induced hypertension (PIH) is a significant complication of pregnancy, contributing to adverse maternal and fetal outcomes. Recent research has illuminated the role of oxidative stress in the pathogenesis of PIH, characterized by an imbalance between reactive oxygen species (ROS) production and antioxidant defenses. This review examines the mechanisms by which oxidative stress contributes to endothelial dysfunction, increased vascular resistance, and systemic inflammation in the context of PIH. By elucidating these mechanisms, the review highlights the critical need for effective strategies to mitigate oxidative stress during pregnancy. Antioxidants have emerged as potential therapeutic agents for managing oxidative stress and preventing PIH. Various antioxidants, including vitamins C and E, omega-3 fatty acids, and coenzyme Q10, have shown p.romise in reducing oxidative damage and improving vascular health during pregnancy. Clinical trials have suggested that supplementation with these antioxidants may enhance endothelial function and lower blood pressure in at-risk pregnant women, thereby decreasing the incidence of PIH and related complications. Keywords: oxidative stress, pregnancy-induced hypertension, antioxidants, endothelial dysfunction, maternal health

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Antioxidant Potential of Cordia dichotoma: A Review

Cited by 4 publications

References 14 publications

Exploring the Therapeutic Potential: Phytochemistry and Pharmacology of Bryophyllum pinnatum

Exploring the Therapeutic Potential: Phytochemistry and Pharmacology of Bryophyllum pinnatum

Antioxidants and the Prevention of Congenital Heart Defects

Oxidative Stress and Pregnancy-induced Hypertension: Antioxidant Solutions

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