Antioxidant properties of a novel flavonoid from leaves of Leucas aspera

Meghashri, S.; Kumar, Hemant; Gopal, Shubha

doi:10.1016/j.foodchem.2010.02.023

Cited by 47 publications

(37 citation statements)

References 20 publications

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“…The total amount of phenolics present in 100 g of A. bettzickiana leaves is found to be 308.526 mg GAE, which is greater than the amount that has been determined from the indigenous leafy vegetable, Mukia maderaspatana 8 (292.392 mg) and that recorded for Leucas aspera 15 (231.000 mg). However, it is less than that reported for Cleome gynandra 16 (321.000 mg).…”

Section: Determination and Characterisation Of The Phenolicsmentioning

confidence: 58%

Foliar Biophenolic Antioxidant Metabolites of Alternanthera bettzickiana

Petrus¹,

Kalpana²,

Devi³

2014

Orient. J. Chem

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Alternanthera bettzickiana (Regel) Nicholson (Family: Amaranthaceae) is an erect herb and an ornamental pot plant, claimed to be useful in purifying and nourishing blood, in addition to the acclaimed soft laxative, galactagogue, antipyretic and wound healing characteristics. The tender leaves and shoots are commonly consumed like vegetable or spinach and in soups, either cooked alone or mixed with other vegetables and served with a staple food like rice or ugali. From the hydrophilic extract of the fresh leaves that exhibited in vitro antioxidant/radical scavenging (ABTS •+ and FRAP assays) and metal (Ferrous ion) chelating capacities, six biophenolic antioxidants, viz.,prop-2-enoic acid and (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid, have been isolated and characterised for the first time adopting extensive chromatographic and spectral studies.

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Section: Determination and Characterisation Of The Phenolicsmentioning

confidence: 58%

Foliar Biophenolic Antioxidant Metabolites of Alternanthera bettzickiana

Petrus¹,

Kalpana²,

Devi³

2014

Orient. J. Chem

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“…It is well known that free radicals can damage DNA, proteins, lipids and carbohydrates within human tissues and cause many diseases, such as cancer, aging, diabetes (Baskar et al, 2004;Meghashri et al, 2010, Halliwell, 1991. Active antioxidant compounds can scavenge free radicals and reactive oxygen species (ROS), prevent the generation of free radicals and ROS, and/or activate a battery of detoxifying proteins to delay or prevent the oxidation of cellular oxidisable substrates.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant activities of Bacillus simplex XJ-25 isolated from sand biological soil crusts and its properties

Wang¹,

Sheng²,

Tian³

et al. 2013

Afr. J. Microbiol. Res.

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XJ-25, a strain with strong antioxidant activity was isolated from sand biological soil crusts in Gurban Tonggut Desert, Xinjiang, China. Strain XJ-25 is closely related to Bacillus simplex through the 16s rDNA sequencing combined with morphological, physiological and biochemical analysis. The medium for optimal antioxidant activity was NB with 1.5 g/L glucose. Based on kinetic assay, antioxidant activity began at early exponential growth phases; maximum activity was reached at the stationary phase. Scavenging effects on DPPH, the hydroxyl and superoxide radicals, Total antioxidant capacity (T-AOC) and protection against lipid damage were evaluated. The main antioxidant compounds were in the extracellular secreted supernatant of XJ-25. The active compounds were very stable at the pH range of 2 to 12, temperature from 40°C to 121°C, as well as in some organic solvents. Thin layer chromatography assay by DPPH scavenging assay show two active spots with Rf values of 0.35 and 0.47 and both of them were ninhydrin positive.

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“…Leucas aspera (LA) Willd. (Labiatae) is commonly called thumbai in India and is found in open, dry, sandy soil, being a weed it is locally abundant (Meghashri et al, 2010). LA is traditionally used for coughs, cold, painful swelling, and in chronic skin eruptions (Kripa et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

“…Compounds isolated from LA include a hydroxyl tetra triacontan-4-one, aliphatic ketones, nicotine, α-farnesene, α-thujene, menthol from leaf volatiles and amyl propionate, isoamyl propionate from flower volatiles. Long chain aliphatic compounds, sterols, triterpenes, phenols, flavonids such as leucasin have been isolated from LA extract (Meghashri et al, 2010). To provide a scientific rationale of this plant, in this study LA extract was investigated for its hepatoprotective activity in d-galactosamine (d-GalN) induced hepatitis model.…”

Section: Introductionmentioning

confidence: 99%