Antioxidant properties of Calendula officinalis L. (Asteraceae) on Fe2+-initiated peroxidation of rat brain mitochondria

Zeinsteger, Pedro Adolfo; Barberón, Javier Leandro; Leaden, Patricio; Palacios, Alejandro

doi:10.1007/s00044-018-2254-1

Cited by 1 publication

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“…Zeinsteger et al [9] reported that Calendula officinalis L. protects rat brain mitochondria from peroxidative damage due to its high content of phenolic acids and flavonoids. Erçetin et al [6] evaluated the antioxidant and cholinesterase inhibitory properties of extracts obtained using different solvents from Calendula arvensis L. and Calendula officinalis L. The highest free radical scavenging activity was observed in the methanolic extracts of Calendula officinalis.…”

Section: Introductionmentioning

confidence: 99%

Modeling and optimizing microwave-assisted extraction of antioxidant compoundsfrom marigold (Calendula officinalisL.) using response surface methodology

Bekdeşer¹

2019

Turk J Chem

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Calendula officinalis L. is a commercially important plant that finds application in the treatment of various diseases in traditional medicine. The total antioxidant capacity, radical scavenging activity, and total phenolic content of marigold extracts were investigated by Folin, CUPRAC, and DPPH assays, respectively. The optimum operating conditions of microwave-assisted extraction (MAE) including temperature, extraction time, solvent-to-solid ratio, and solvent concentration were ascertained by employing response surface methodology (RSM). The solvent (ethanol) concentration was the most significant operating factor among all responses of MAE. At the optimum extraction conditions, the maximum yield of total phenolic content, total antioxidant capacity, and radical scavenging activity obtained experimentally were very close to their predicted values, thus showing the suitability of the model used and the success of RSM in optimizing the extraction conditions. Chromatographic analysis of marigold extract was performed by UPLC-PDA-ESI-MS/MS system and chlorogenic acid was the main component (1742.50 ± 42.23 µ g/g DS).

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Section: Introductionmentioning

confidence: 99%

Modeling and optimizing microwave-assisted extraction of antioxidant compoundsfrom marigold (Calendula officinalisL.) using response surface methodology

Bekdeşer¹

2019

Turk J Chem

View full text Add to dashboard Cite

show abstract

Antioxidant properties of Calendula officinalis L. (Asteraceae) on Fe2+-initiated peroxidation of rat brain mitochondria

Cited by 1 publication

References 52 publications

Modeling and optimizing microwave-assisted extraction of antioxidant compoundsfrom marigold (Calendula officinalisL.) using response surface methodology

Modeling and optimizing microwave-assisted extraction of antioxidant compoundsfrom marigold (Calendula officinalisL.) using response surface methodology

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