Antioxidant properties of gold nanozyme: A review

Sharifi, Majid; Faryabi, Kousar; Talaei, Amir Jouya; Shekha, Mudhir Sabir; Ale-Ebrahim, Mahsa; Salihi, Abbas; Nanakali, Nadir Mustafa Qadir; Aziz, Falah Mohammad; Rasti, Behnam; Hasan, Anwarul; Falahati, Mojtaba

doi:10.1016/j.molliq.2019.112004

Cited by 74 publications

(39 citation statements)

References 97 publications

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“…Monometal nanozymes could be prepared through preformed-seed-mediated growth [ 68 ], high-temperature reduction method [ 2 , 69 – 71 ], electrochemical synthesis, photochemical method, biosynthesis [ 72 , 73 ], and spatially confined medium/template approach [ 74 ]. With different methods, various forms of noble metal nanomaterials (e.g., nanoparticles [ 14 , 15 ], nanoclusters [ 10 ], nanorods [ 75 ], nanosheets [ 76 ], nanocubes) could be obtained. The preformed‐seed‐mediated growth is feasible for size control by changing the concentration and nature of seeds in the growth solution [ 77 ].…”

Section: Preparing Diverse Nanozymes With Constructive Featurementioning

confidence: 99%

A Review on Metal- and Metal Oxide-Based Nanozymes: Properties, Mechanisms, and Applications

et al. 2021

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Since the ferromagnetic (Fe3O4) nanoparticles were firstly reported to exert enzyme-like activity in 2007, extensive research progress in nanozymes has been made with deep investigation of diverse nanozymes and rapid development of related nanotechnologies. As promising alternatives for natural enzymes, nanozymes have broadened the way toward clinical medicine, food safety, environmental monitoring, and chemical production. The past decade has witnessed the rapid development of metal- and metal oxide-based nanozymes owing to their remarkable physicochemical properties in parallel with low cost, high stability, and easy storage. It is widely known that the deep study of catalytic activities and mechanism sheds significant influence on the applications of nanozymes. This review digs into the characteristics and intrinsic properties of metal- and metal oxide-based nanozymes, especially emphasizing their catalytic mechanism and recent applications in biological analysis, relieving inflammation, antibacterial, and cancer therapy. We also conclude the present challenges and provide insights into the future research of nanozymes constituted of metal and metal oxide nanomaterials.

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Section: Preparing Diverse Nanozymes With Constructive Featurementioning

confidence: 99%

A Review on Metal- and Metal Oxide-Based Nanozymes: Properties, Mechanisms, and Applications

et al. 2021

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“…Some of these studies are more generic [80][81][82][83][84], while some others are specific for gold nanomaterials [14], metal-organic frameworks (MOFs) [85,86] or metal-oxide nanomaterials (MONMs) [87]. Although similar reviews have been published elsewhere, e.g., covering either the factors controlling the activity of gold nanozymes [88] or their potential biosensing and therapeutic applications [89], this review is presented as a comprehensive analysis intending to link both sections, from the fabrication of gold nanozymes, their catalytic mechanisms, potential applications and obstacles in the biomedical field.…”

Section: Catalytic Properties Of Gold Nanoparticlesmentioning

confidence: 99%

Gold Nanozymes: From Concept to Biomedical Applications

et al. 2020

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In recent years, gold nanoparticles have demonstrated excellent enzyme-mimicking activities which resemble those of peroxidase, oxidase, catalase, superoxide dismutase or reductase. This, merged with their ease of synthesis, tunability, biocompatibility and low cost, makes them excellent candidates when compared with biological enzymes for applications in biomedicine or biochemical analyses. Herein, over 200 research papers have been systematically reviewed to present the recent progress on the fundamentals of gold nanozymes and their potential applications. The review reveals that the morphology and surface chemistry of the nanoparticles play an important role in their catalytic properties, as well as external parameters such as pH or temperature. Yet, real applications often require specific biorecognition elements to be immobilized onto the nanozymes, leading to unexpected positive or negative effects on their activity. Thus, rational design of efficient nanozymes remains a challenge of paramount importance. Different implementation paths have already been explored, including the application of peroxidase-like nanozymes for the development of clinical diagnostics or the regulation of oxidative stress within cells via their catalase and superoxide dismutase activities. The review also indicates that it is essential to understand how external parameters may boost or inhibit each of these activities, as more than one of them could coexist. Likewise, further toxicity studies are required to ensure the applicability of gold nanozymes in vivo. Current challenges and future prospects of gold nanozymes are discussed in this review, whose significance can be anticipated in a diverse range of fields beyond biomedicine, such as food safety, environmental analyses or the chemical industry.

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“…Then, the slide coated with isolates underwent Gram staining. A further confirmatory study of the morphology of the isolates was conducted using Kovacs reagent, methyl red, glucose broth, and hydrogen peroxide in appropriate quantities, added dropwise to the nutrient broth containing the isolates [ 11 ]. A positive result of this biochemical test gives us an idea about the sample’s physiological status, which facilitates further processing.…”

Section: Methodological Analysismentioning

confidence: 99%

“…The selected isolate was inoculated in 1000 mL of sterile freshly prepared nutrient broth [ 11 ]. Then, the flask was placed in a rotating shaker (REMI, RS.24BL 11/07, India) at 200 rpm and incubated for 48 h at room temperature.…”

Section: Methodological Analysismentioning

confidence: 99%

Bacillus-Mediated Silver Nanoparticle Synthesis and Its Antagonistic Activity against Bacterial and Fungal Pathogens

Kabeerdass¹,

Otaibi

Rajendran³

et al. 2021

Antibiotics

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In this article, the supernatant of the soil-borne pathogen Bacillus mn14 was used as the catalyst for the synthesis of AgNPs. The antibacterial and antifungal activity of Bs-AgNPs was evaluated, in which S. viridans and R. solani showed susceptibility at 70 µL and 100 µL concentrations. Enzyme properties of the isolates, according to minimal inhibitory action and a growth-enhancing hormone–indole acetic acid (IAA) study of the isolates, were expressed in TLC as a purple color with an Rf value of 0.7. UV/Vis spectroscopy revealed the presence of small-sized AgNPs, with a surface plasmon resonance (SPR) peak at 450 nm. The particle size analyzer identified the average diameter of the particles as 40.2 nm. The X-ray diffraction study confirmed the crystalline nature and face-centered cubic type of the silver nanoparticle. Scanning electron microscopy characterized the globular, small, round shape of the silver nanoparticle. AFM revealed the two-dimensional topology of the silver nanoparticle with a characteristic size ranging around 50 nm. Confocal microscopy showed the cell-wall disruption of S. viridans treated with Bs-AgNPs. High-content screening and compound microscopy revealed the destruction of mycelia of R. solani after exposure to Bs-AgNPs. Furthermore, the Bs-AgNPs cured sheath blight disease by reducing lesion length and enhancing root and shoot length in Oryza sativa seeds. This soil-borne pathogen Bacillus-mediated synthesis approach of AgNPs appears to be cost-efficient, ecofriendly, and farmer-friendly, representing an easy way of providing valuable nutritious edibles in the future.

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Antioxidant properties of gold nanozyme: A review

Cited by 74 publications

References 97 publications

A Review on Metal- and Metal Oxide-Based Nanozymes: Properties, Mechanisms, and Applications

A Review on Metal- and Metal Oxide-Based Nanozymes: Properties, Mechanisms, and Applications

Gold Nanozymes: From Concept to Biomedical Applications

Bacillus-Mediated Silver Nanoparticle Synthesis and Its Antagonistic Activity against Bacterial and Fungal Pathogens

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