Antioxidant Properties of Methanol Extract of Parquetina Nigrescens in Ulcerated Rats

Anti-diabetic Activity of Convallatoxin Isolated from the Root Bark of Parquetina nigrescens (Afzel.) Bullock (Asclepiadaceae)

“…The root bark is used in the management of diabetes mellitus in Akure, Ondo State of Nigeria (Personal Communication). Its analgesic, anti-inflammatory, antipyretic, antiulcerogenic, antioxidant, anti-sickling, antimicrobial, sympathomimetic, haematological, uterotonic and cytotoxic activities have been reported [15][16][17][18][19][20][21][22]. The aqueous leaf extract has been reported for anti-diabetic effect in alloxaninduced diabetic rats and it was also reported for its improvement in sexual activity in rats induced with sexual dysfunction [23,24].…”

Antidiabetic and antihyperlipidemic effects of aqueous extract of Parquetina nigrescens in streptozotocin–nicotinamide induced type 2 diabetic rats

“…Common names for this plant include; Ogbo in Yoruba, kwankwanin in Hausa and Mgbidimgbe in Igbo, Nigeria [7]. The plant is used locally to treat fever and pains, menstrual disorders, helminthiasis, diabetes, rickets, diarrhea, wounds and sexual dysfunction [8,9,10]. Various parts of the plant have been documented to be safe [7,11,12] and to have antioxidant, erythrocyte membrane stabilizing, antilipogenic, antiulcer, analgesic, anti-inflammatory and antipyretic activities [9,13,14,15].…”

“…The plant is used locally to treat fever and pains, menstrual disorders, helminthiasis, diabetes, rickets, diarrhea, wounds and sexual dysfunction [8,9,10]. Various parts of the plant have been documented to be safe [7,11,12] and to have antioxidant, erythrocyte membrane stabilizing, antilipogenic, antiulcer, analgesic, anti-inflammatory and antipyretic activities [9,13,14,15]. The plant has also been reported to ameliorate alloxan-induced type 1 diabetes mellitus (T1DM) in rats [16].…”

Haematopoietic Activity of Parquentina Nigriscence (Afzel) Bullock (Asclepiadaceae) Leaf Methanol Extract in Rats

“…Parquentina nigriscence is a plant used in fork medicine in many countries. Parquentina nigriscence occurs largely in all parts of Africa, from Senegal, Sudan and South through Central and East Africa to Zambia Angola and Eastern Zimbabwe [1]. Some scientific findings have confirmed the efficacy of this plant in the treatment of some diseases such as anemia [3].…”

“…Regardless of the fact that many causes of anaemia have been identified worldwide, it is agreed that nutritional deficiency due primarily to low bioavailability of dietary iron accounts for more than half the total number of cases. Haematological parameters screening are the most convenient screening methods in anaemia [1]. Parquentina nigriscence is a plant used in fork medicine in many countries.…”