Antioxidant rich medicinal plants as a potential candidate to treat gastric ulcer

Abstract

Oxidative stress is a key cause of gastrointestinal disorders, primarily stomach ulcers. Multiple intrinsic and extrinsic mechanisms caused the body to produce reactive oxygen species (ROS). The body's antioxidant defense system protects against these reactive species. When the degree of ROS production exceeds the normal range, the body's natural defense system fails to neutralize these dangerous free radicals, necessitating need foran exogenous source of natural antioxidants. Natural herbal remedies have been widely employed as antioxidants to relieve oxidative stress in gastric ulcers. Polyphenols, tannins, essential oils, flavonoids, notably quercetin, carotenoids, vitamin C, vitamin A, and minerals are among the molecules of immense interest in bioassays due to their significant antioxidant effects. In the present review, several natural anti-ulcer medicinal plants along with their antioxidative mechanism have been reported. Electronic databases including PubMed, Google Scholar and Scopus were explored to identify the antioxidant and gastroprotective potential of all the plants.

Novel acaricidal and growth-regulating activity of Aloe vera and Rheum rhabarbarum extracts and their oil/water nanoemulsions against the camel tick, Hyalomma dromedarii

“…Consequently, searching for eco-friendly acaricides is a pressing need 12 , 16 , 67 . Besides their pesticidal effects, botanicals have fungicidal, bactericidal, and antioxidant properties; therefore, they are used in medicine and cosmetics 15 , 24 , 32 , 49 . There are few studies on the efficacy of herbal extracts against H. dromedarii 10 , 78 – 81 and very rare studies tested their effect on its reproductive potential 50 .…”

“…There is a persistent demand for searching for eco-friendly control strategies using Plant-based resources (botanicals), biological control agents, vaccination, photosensitizers, and safe acids 12 – 18 to reduce the health and environmental hazards resulting from repeated applications of conventional pesticides 19 – 22 . Botanicals have been widely used, since ancient civilizations 23 , because of their high efficacy against pests and illness 14 , 24 – 32 , relative safety to non-target organisms 27 , 33 , 34 , rapid biodegradation, and prevention of development of resistance in pests because of their various active substances and mechanisms of actions 19 – 21 , 35 . Against pests of medical and veterinary importance, botanicals induce ovicidal 36 , 37 , larvicidal 38 – 43 , adulticidal 36 , 44 – 48 , repellent 36 , 45 , 46 , and insect growth regulating (IGR) effects 38 , 49 – 51 .…”