Antioxidant-rich phytochemicals in miracle berry (Synsepalum dulcificum) and antioxidant activity of its extracts

Du, Liqing; Shen, Yixiao; Zhang, Xiumei; Prinyawiwatkul, Witoon; Xu, Zhimin

doi:10.1016/j.foodchem.2013.12.072

Cited by 70 publications

(59 citation statements)

References 24 publications

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“…In another study, berry extract was shown to have strong antioxidant and anticancer activities [19,20,21,22]. Here we confirm these reported in vitro effects using a different cell-based system and the extracts of three kinds of berries containing phenolic compounds.…”

Section: Discussionsupporting

confidence: 88%

Protective Effects of Berry Extracts on Hydrogen Peroxide-induced Rat Brain Neuronal Cell Damage in vitro

Jeong¹,

Jang²,

Kum³

et al. 2014

JFNR

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The purpose of this study was to evaluate the antioxidative activities and protective effects of boysenberry, black currant, and blueberry extracts on neuronal cells. We found that berry extracts had different levels of antioxidant efficacy in various assays, including cell viability assays using 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl-tetrazoliumbromide (MTT). In addition, reactive oxygen species (ROS) were measured using 2',7'-dichlorofluorescein diacetate (DCF-DA) and flow cytometry analysis. Fruit extracts possessed strong antioxidant activities as measured using the malondialdehyde (MDA) assays. These extracts effectively inhibited lipid peroxidation. Black currant fruit extract significantly reduced intracellular ROS accumulation resulting from hydrogen peroxide treatment in PC12 cells. Black currant fruit more effectively inhibited lactate dehydrogenase (LDH) release into the medium than other tested fruit extracts did. The present results indicate that fruit extracts have the potential to protect neurons from hydrogen peroxide-induced cell damage and should be considered as a prospective functional food and therapeutic product.

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Section: Discussionsupporting

confidence: 88%

Protective Effects of Berry Extracts on Hydrogen Peroxide-induced Rat Brain Neuronal Cell Damage in vitro

Jeong¹,

Jang²,

Kum³

et al. 2014

JFNR

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“…But pure ethanol extract also has very impressive presented with DPPH free radical scavenging ability, suppose this result is related to high flavonoid content in pure ethanol extract. Du Liqing et al and Inglett and Chen reported the DPPH free radical scavenging of the miracle fruit seed extracts are 54.3 and 49.45% [1], [2], and in this study, we observed higher antioxidant ability. …”

Section: B the Antioxidant Ability Of Miracle Fruit Seeds Extract Insupporting

confidence: 66%

“…The ABTS ability was more than 70% of miracle fruit seed crude extract supernatants by using sodium acetate buffer (pH 6.0) and 50% ethanol as extraction solvents (Fig. 5) , which was triple that of the previous report (18%) [2].…”

Section: The Antioxidant Ability Of Miracle Fruit Seeds Extract Inmentioning

confidence: 51%

“…In a previous study, Du Liqing et al reported total phenolic content of 3.067μg GAE/mg-Fw in the methanolic extracts obtained from miracle fruit seeds [2]. But methanol is not suitable extraction solvent for food application.…”

Section: A Total Phenolic and Flavonoid Content Of Miracle Fruit Seementioning

confidence: 99%

“…Besides the breeding use, most of the seeds are taken into bio-composting field. However, there are some researches described with the promising use for existence of steroids, phenols, and flavonoids as well [1], [2]. For the demand of aging society, these substances have the ability to overact the free radicals, regulate the immunity, anti-inflammation, cardiovascular protection and cancer prevention.…”

Section: Introductionmentioning

confidence: 99%

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Polyphenol Measurement and Antioxidant Activity of Miracle Fruit

Cheng¹,

Huang²,

Lin³

et al. 2015

IJCEA

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Abstract-Miracle fruit has unique protein which can make sour flavors to sweet, and the bright red skin might be a natural pigment. After the harvest of miracle fruit, removal of fruit skin, fruit meat, the fruit seeds become natural side product using for biofertilizer. Recently, a growing research reports focus on the investigation of fruit seeds for screening potential antioxidants, such as steroids, phenols, and flavonoids as well. In this research, we verity miracle fruit seed is great multi-antioxidant source by different extraction solution. 3μg (GAE)/mg total phenolic and 3.1μg (RUE)/mg flavonoid content was measured when the miracle fruit was extracted by acetic acid buffer with 20mM at pH6.0 and pure ethanol. The antioxidation ability of DPPH and ABTS free radical scavenging was over 70%, chelating effect of ferrous ions reached 80%.Index Terms-Miracle fruit, fruit seed, total phenolics, antioxidant activity.

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Comparative assessment of chemical compositions, antioxidant and antimicrobial activity in ten berries grown in China

Liang

Xin

2019

Flavour & Fragrance J

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Berries have many biological and physiological functions such as antioxidant, antibacterial and anti-inflammatory, and become a more popular food in China. Water-soluble polyphenols are their main functional active substances, and aroma components contribute to the flavour. The contents of total phenol and volatile organic compounds (VOCs) in ten berries grown in Northeast China were determined. Their antioxidant and antimicrobial activities were also investigated. Ribes rubrum L. and Rubus glaucus showed a higher antioxidant capacity. Ribes rubrum L. and Lonicera caerulea have a broader antibacterial spectrum. There is a correlation between the content of hydroxyl compounds in radical antioxidant activity. The metabolic pathways of polyphenols and VOCs are correlated, indicating a rapid evaluation of the biological activity of berries using the determination of volatile components. K E Y W O R D Sberries, VOCs, antioxidant, antimicrobial activity, correlation analysis

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Antioxidant-rich phytochemicals in miracle berry (Synsepalum dulcificum) and antioxidant activity of its extracts

Cited by 70 publications

References 24 publications

Protective Effects of Berry Extracts on Hydrogen Peroxide-induced Rat Brain Neuronal Cell Damage in vitro

Protective Effects of Berry Extracts on Hydrogen Peroxide-induced Rat Brain Neuronal Cell Damage in vitro

Polyphenol Measurement and Antioxidant Activity of Miracle Fruit

Comparative assessment of chemical compositions, antioxidant and antimicrobial activity in ten berries grown in China

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