Antioxidant Status in Adolescents of Small Siberian Ethnoses

Колесникова, Л. И.; Darenskaya, M. A.; Rychkova, L. V.; Grebenkina, Lyudmila; Semenova, Natalya; Гаврилова, Оксана

doi:10.1134/s0022093018020060

Cited by 3 publications

(2 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The dependence of the AO system of the human organism on the climatic factors of the environment was shown in extreme climate conditions. 7 Apparently, the decrease in AOA and ARA in blood plasma of Altaic women in the southern Altai highlands was determined by unfavorable…”

Section: Discussionmentioning

confidence: 99%

Untitled

2020

MOJAP

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Untitled

2020

MOJAP

View full text Add to dashboard Cite

“…В последние годы с целью оценки глубины и выраженности патологического процесса в клинической практике активно изучаются процессы свободно радикального ПОЛ. Повышенный интерес вызван тем, что процессы ПОЛ играют не только важную роль в нормальной физиологии клетки, но и выступают как ранние ключевые звенья патогенеза многих заболеваний и острых состояний [2][3][4][5][6]. В связи с наличием большого количества факторов активации процессов ПОЛ в ходе оперативного вмешательства, общего обезболивания, а также в ближайшем послеоперационном периоде знания об этих процессах приобретают особую актуальность для врача -анестезиолога-реаниматолога [7,8].…”

Section: Introductionunclassified

Potentials of intravenous laser blood irradiation to correct peroxidation and antioxidant activity as a result of surgical distress

et al. 2021

View full text Add to dashboard Cite

Purpose: to reveal protective effects of intravenous low-level laser blood irradiation (ILBI) during surgical interventions at the gallbladder as well as to study the state of antioxidant activity, lipid peroxidation and endogenous intoxication.Material and methods. In the perioperative period, 40 patients from the main group (I) had traditional treatment which included pharmacological preparations and sessions of intravenous laser blood irradiation. 45 patients from the control group (II) had only traditional (pharmacotherapeutic) treatment. In both groups during surgery, the anesthetic protection consisted of classical neuroleptanalgesia. The age of patients in both groups did not differ significantly. Intravenous laser blood irradiation was done with helium-neon laser “Atoll” 632 nm (Fokon Ltd, St-Petersburg, Russia). During surgery, three irradiation sessions were performed at radiation power of 20 mW and exposure 15 minutes at various stages of surgery: 30 minutes before induction of anesthesia, at the traumatic stage and 30 minutes before the expected finish of the surgery. Ceruloplasmin and transferrin levels in the blood plasma were assessed with the electron paramagnetic resonance technique. The ratio of ceruloplasmin/transferrin which characterizes the level of antioxidant activity was also established. The level of endogenous intoxication was assessed using the previously published technique. The quantitative characteristics of endogenous intoxication by this technique is the value of optical density (D280) and total optical density of components related to high molecular weight and low molecular weight fractions.Results. ILBI sessions in patients neutralize changes in the level of ceruloplasmin and transferrin in blood. The data obtained also confirm ILBI protective effects at protein SH-groups or activation of the restoration of protein SH-groups that were damaged by oxidation as a result of surgical aggression and trauma.Conclusion. The protective effect of intravenous laser blood irradiation in addition to the standard preoperative therapy optimizes pharmacological anesthetic protection during surgery under the existing traditional schemes of combined general anesthesia.

show abstract