“…Polyphenols digestion consists of absorption in the intestine along with the DFs and releasing from the matrix formed with fibers into the colon due to the favorable antioxidant environment created by the bacteria (Kawabata, Yoshioka, & Terao, 2019;Saura-Calixto, 2011). Antioxidants contribute to the prevention of various cancer types, cardiovascular diseases, neurodegenerative diseases, and several dermal disorders (Kawabata et al, 2019;Seifried, Harrison, & Seifried, 2017). Grape seeds are rich in monounsaturated and unsaturated fatty acids, one of them being the linoleic acid (Lachman et al, 2015;Pérez-Navarro, Da Ros, et al, 2019), whereas grape peels have high amounts of saturated acids mainly stearic, palmitic, and lignoceric (Pérez-Navarro, Da Ros, et al, 2019).…”