2004
DOI: 10.1053/j.ajkd.2003.09.011
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Antiphospholipid antibodies are associated with an increased risk for chronic renal insufficiency in patients with lupus nephritis

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Cited by 137 publications
(92 citation statements)
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“…The risk for progression to end-stage kidney disease secondary to lupus nephritis (LN) in native kidneys has been estimated at up to 26%. 1,2 The outcome of the renal disease, as well as of the renal transplantation for recipients with LN depends on the population studied, race/ethnicity, geographical origin, socioeconomic conditions, donor-related factors, among others. [3][4][5] In addition, the reported recurrence rate of LN after transplantation varies in different series.…”
Section: Introductionmentioning
confidence: 99%
“…The risk for progression to end-stage kidney disease secondary to lupus nephritis (LN) in native kidneys has been estimated at up to 26%. 1,2 The outcome of the renal disease, as well as of the renal transplantation for recipients with LN depends on the population studied, race/ethnicity, geographical origin, socioeconomic conditions, donor-related factors, among others. [3][4][5] In addition, the reported recurrence rate of LN after transplantation varies in different series.…”
Section: Introductionmentioning
confidence: 99%
“…2,3 Indeed, it is likely that many examples of what has been termed in the past lupus vasculopathy or lupus vasculitis 4 were in fact examples of antiphospholipid syndrome, because most were described in the era before widespread recognition of the syndrome as a complication of lupus. The following case is an apt example of this entity, both clinically and morphologically.…”
mentioning
confidence: 99%
“…Антифосфолипидные антитела (аФЛ) коррелируют с активностью СКВ, тромбозами, необратимым повреждени-ем внутренних органов и осложнениями беременности при СКВ [42][43][44]. Предполагают, что существенная роль при раннем отторжении трансплантата у пациентов с СКВ и пе-ресаженной почкой принадлежит аФЛ [45].…”
Section: оценка лабораторных параметровunclassified
“…Риск двукратного повышения уровня сывороточного креатинина варьирует от 7,4 до 8,5% к 5-му году болезни и от 14,3 до 18,2% -к 10-му году. Показано, что возраст, этническая принадлежность, уровень сывороточного креатинина, C3-компонента комп-лемента, АГ, данные биопсии почек (индекс активности и хронизации) ассоциируются с 5-летней выживаемостью па-циентов с волчаночным нефритом [41][42][43][44][45][46][47][48].…”
Section: почкиunclassified