Antiphospholipid syndrome and acute myocardial infarction: Treatment with thrombectomy and abciximab

Chronic total occlusions of the right coronary and left anterior descending coronary arteries in a young adult patient with antiphospholipid syndrome

“…The cause of severe CAD in the present case was not apparent. A young man with AMI and APS but no major coronary risk factors showed no significant coronary plaque on IVUS imaging after thrombus aspiration in the infarct-related artery [7], while a young woman with SLE and APS had diffuse coronary atherosclerosis progression for her age in the non-occluded coronary arteries on IVUS imaging [8]. APS is classified as primary APS without an underlying systemic autoimmune disease and secondary APS with the presence of another systemic autoimmune disease.…”

“…Thrombectomy [7], stent implantation [4], or coronary bypass surgery [9] for the treatment of AMI in patients with APS has been reported. However, there are no reports of the treatment of CTO lesions in patients with APS.…”

Infarto agudo de miocardio como manifestación inicial de síndrome antifosfolípido primario: Reporte de Caso

“…En general, el abordaje terapéutico es similar a los casos de IAM sin SAF y los resultados son satisfactorios, pero debe recordarse que en estos casos hay una patología subyacente de base, de naturaleza trombótica y recurrente y que la anticoagulación hace parte de su manejo esencial para el resto de sus vidas (12)(13)(14)(15)(16).…”

Acute inferior myocardial infarction with severe thrombus formation in a young male patient with primary antiphospholipid syndrome

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Antiphospholipid syndrome (AS) or antiphospholipid body syndrome is associated with arterial or venous thrombosis. This syndrome is diagnosed with determining serum antiphospholipid bodies which lead to the clinical events such as arterial or venous thrombosis [1][2][3][4][5][6][7][8][9][10]. Pathophysiology of disease is associated with activating coagulation cascade or inhibiting protein S and/or protein C by antiphospholipid bodies.

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