Antiphytopathogenic activity ofPsoralea glandulosa(Fabaceae) againstBotrytis cinereaandPhytophthora cinnamomi

Abstract

The resinous exudate, three meroterpenes, namely bakuchiol (1), 3-hydroxybakuchiol (2), 12-hydroxyisobakuchiol (3), and one furanocoumarin, psoralen (4), were isolated from the leaves of culen (Psoralea glandulosa). In addition to these, two semi-synthetic derivatives, bakuchiol acetate (5) and bakuchiol methyl eter (6), were obtained from 1, and were subsequently evaluated in vitro for the inhibitory effect of resin and compounds on the mycelial growth of Botrytis cinerea Pers.: Fr. and Phytophthora cinnamomi Rands. The resinous exudate inhibited the mycelial growth of both the pathogens, while bakuchiol (1) exhibited an inhibitory effect on the mycelial growth of B. cinerea up to 94% at a concentration of 150 mg/L and psoralen (4) reduced the mycelial growth of P. cinnamomi up to 80% at a concentration of 150 mg/L. These compounds have the ability of blocking the development of mycelial growth and may be used as a potential biopesticide in the agricultural sector once the in vivo test results have been validated.

Biological Properties and Absolute Configuration of Flavanones From Calceolariathyrsiflora Graham

“…A modified Folin-Ciocalteu (FC) method ( Madrid et al., 2015 ) was used. The sample solution (15 μ L) was mixed with distilled water (15 μ L) and 0.2 N FC reagent (150 μ L).…”

Sonochemical Synthesis of 2’-Hydroxy-Chalcone Derivatives with Potential Anti-Oomycete Activity

“…Mycelial discs (4 mm in diameter) of test fungi grown on rye B agar [ 38 ] were cut from the margins of the colony and placed on the same medium containing different concentrations of the test oxyalkyl chalcones (12.5–400 µg/mL). After incubation at 20 °C for seven days, radial mycelial growth was measured and was compared with the controls [ 39 ]. Control plates were treated with difenoconazole and metalaxil.…”

A Review of the Pharmacological Properties of Psoralen

“…Chiang et al found that psoralen displayed an antibacterial effect on mycobacterium tuberculosis H37Rv ( Chiang et al, 2010 ). Villegas observed that psoralen inhibited the growth of P. cinnamomi mycelia ( Villegas et al, 2015 ), indicating that psoralen has the potential to be a biological pesticide. Li et al found that psoralen inhibited the formation of biofilms, eliminated established biofilms and reduced their viability ( Li et al, 2018 ).…”