Antiplaque efficacy of tooth and gums tonic, Hiora-GA gel, and Spirogyl Gum Paint in comparison with chlorhexidine M gel: A double-blind randomized control trial

Abstract

Objective:To compare the efficacy of three different herbal products (Tooth and Gums Tonic, Hiora-GA gel, and Spirogyl Gum paint) in reducing plaque, gingival inflammation and bacterial count in comparison with chlorhexidine M gel among participants with moderate to severe periodontitis.Materials and Methods:A total of eighty participants with moderate to severe periodontitis were initially recruited after obtaining their informed consent. All participants were offered scaling and polishing on the first visit to remove visible calculus. Then, these participants were randomly divided into four groups of twenty participants each using block randomization method. Participants in Group 1, 2, 3, and 4 were given chlorhexidine M gel, Hiora-GA gel, Spirogyl Gum paint, and Tooth and Gums Tonic, respectively. All participants were instructed to brush their teeth twice day with a soft bristled toothbrush and their regular fluoridated toothpaste. They were instructed to apply the respective gels twice a day according to the manufacturer's guidelines. The posttreatment follow-up examinations for gingival and plaque changes were assessed after 30, 60, and 90 days by three trained and calibrated investigators using gingival and plaque index. The investigators and statistician were blind about group allocation. The supragingival plaque samples were collected before and 90 days after treatment from the buccal surfaces of maxillary right first permanent molar of each participant for microbial analysis.Results:The mean plaque, gingival scores significantly decreased at different intervals following intervention in all groups. The bacterial counts also significantly reduced postintervention with no significant difference in the efficacy of these products compared to chlorhexidine.Conclusion:All three herbal products were found to be effective when used along with oral prophylaxis. Hence, they can all be used as alternates to chlorhexidine in the management of periodontal diseases.

Myrrh Oil Reduces Gingival Inflammation and Inhibits Gram Negative Dental Plaque Bacteria at Early Stages – A Randomized Control Trial

“…We found a significant antibacterial effect of Myrrh oil, a plant extract leading to reduction of bacterial count (Gram -ve microorganisms) 7 days after the intervention compared to baseline levels. This finding was in accordance with a study by Sukhabogi et al [23] who compared three different herbal products with a chlorhexidine gel and found to be effective in reducing plaque and gingival scores. Al-Mobeeriek et al [24] in an animal study reported that myrrh suspension promotes healing and repair of damaged tissue in comparison to Chlorhexidine and Tetracycline.…”

Beneficial Role of Antioxidant Secondary Metabolites from Medicinal Plants in Maintaining Oral Health

“…The effect of Eucalyptus globulus extract added as an ingredient in herbal product (tooth and gums tonic) was compared with chlorhexidine M gel in double-blind RCT and showed a decrease in mean gingival and plaque value at different intervals. It was observed to be equally effective in comparison to chlorohexidine with no statistically significant difference (p = 0.001) [158].…”

Clinical Effectiveness of Herbal Oral Care Products in Periodontitis Patients: A Systematic Review

“…The Cohen’s kappa values for inter-reviewer agreement for the first and second rounds of study selection were 0.94 and 0.98, respectively. The reasons of exclusion were: (1) inclusion of human subjects with no diagnosis of periodontitis [ 29 , 30 , 31 , 32 , 33 ], (2) periodontal diagnosis based on partial clinical examination [ 21 ], (3) study protocol [ 34 ], (4) use of herbal gels subgingivally as local-drug delivery [ 35 , 36 , 37 , 38 , 39 , 40 ], (5) non-English publication [ 41 ] and (6) no full text available [ 42 ]. Meta-analysis was not possible due to the increased heterogeneity in the disease/health definitions, periodontal evaluation, follow-up times, study protocols, and the variety of herbs.…”