Antiplatelet Treatment Patterns and Outcomes for Secondary Stroke Prevention in the United Kingdom

Liu, Xuejun; Jiang, Jenny; Li, Danshi; Horrow, Jay; Tamada, Hiroshi; Kahl, Anja; Hariharan, Vignesh; Avinav, Ankur; Li, Xiaoyan

doi:10.1007/s40119-023-00332-7

Cited by 1 publication

(2 citation statements)

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“…Similarly, other studies reported high rates of prophylaxis and antiplatelet medication prescription upon discharge, with DVT prophylaxis performed in over 85% and the antiplatelet drugs prescribed for more than 70% of cases [32]. In the UK, over 80% of at-risk patients of recurrent stroke receive antiplatelet treatment [33]. Global surveys indicate that hospitals administer antiplatelet agents and statins to 50-60% of patients upon discharge [34].…”

Section: Discussionmentioning

confidence: 91%

“…Global surveys indicate that hospitals administer antiplatelet agents and statins to 50-60% of patients upon discharge [34]. This underscores the importance of adhering to guidelines for prophylactic antithrombotic therapy to reduce the risk of recurrent vascular events, thereby enhancing care quality for AIS and TIA patients while mitigating associated costs [32][33][34][35][36].…”

Section: Discussionmentioning

confidence: 99%

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Length of Hospitalization and Mortality among Stroke Patients before and after the Implementation of a Specialized Unit: A Retrospective Cohort Study Using Real-World Data from One Reference Hospital in Southern Brazil

Poll,

Martins,

Anschau

et al. 2024

Healthcare

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Stroke constitutes a significant global cause of mortality and disability. The implementation of stroke units influences hospital quality indicators, guiding care management. We aimed to compare hospital length of stay (LOS), in-hospital mortality, and post-discharge mortality between stroke patients admitted in the pre- and post-implementation periods of a stroke unit in a public hospital in southern Brazil. This retrospective cohort study used real-world data from one reference hospital, focusing on the intervention (stroke unit) and comparing it to the general ward (control). We analyzed the electronic medical records of 674 patients admitted from 2009 to 2012 in the general ward and 766 patients from 2013 to 2018 in the stroke unit. Admission to the stroke unit was associated with a 43% reduction in the likelihood of prolonged hospitalization. However, there was no significant difference in the risk of in-hospital mortality between the groups (Hazard ratio = 0.90; Interquartile range = 0.58 to 1.39). The incidence of death at three, six and twelve months post-discharge did not differ between the groups. Our study results indicate significant improvements in care processes for SU patients, including shorter LOS and better adherence to treatment protocols. However, our observations revealed no significant difference in mortality rates, either during hospitalization or after discharge, between the SU and GW groups. While SU implementation enhances efficiency in stroke care, further research is needed to explore long-term outcomes and optimize management strategies.

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Section: Discussionmentioning

confidence: 91%