2018
DOI: 10.18203/2319-2003.ijbcp20185107
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Antiproliferative effects of Vanilla planifolia leaf extract against breast cancer MCF-7 cells

Abstract: Background: Breast cancer is the most common cancer disease among females in India and worldwide. This needs a critical research for finding the drugs to treat breast cancer with less side effects. The aim of the present study is to reveal the anti-proliferative effects of vanilla extract against MCF-7 cells.Methods: To reveal anti proliferative effects of vanilla leaf extract, MTT assay, cell cycle analysis and DNA fragmentation assay was performed as per standard protocols.Results: MTT assay showed decrease … Show more

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Cited by 3 publications
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“…Other orchid extracts that are effective against breast cancer (MCF-7) are those from Eulophia nuda tubers [141], leaves of Aerides odorata [142], and leaves of Vanilla [143]. It is hypothesized that the cytotoxic activity is related to the synergistic action of the phytoconstituents present in these species [141].…”
Section: The Anticancer Activity Of Plant Extracts From Orchidaceaementioning
confidence: 99%
“…Other orchid extracts that are effective against breast cancer (MCF-7) are those from Eulophia nuda tubers [141], leaves of Aerides odorata [142], and leaves of Vanilla [143]. It is hypothesized that the cytotoxic activity is related to the synergistic action of the phytoconstituents present in these species [141].…”
Section: The Anticancer Activity Of Plant Extracts From Orchidaceaementioning
confidence: 99%