Antipsychotic-Free Status in Community-Dwelling Patients With Schizophrenia in China

Hou, Cai‐Lan; Chen, Miao-Yang; Cai, Meiying; Chen, Zi-Lang; Cai, Shou-Bin; Xiao, Yao; Jia, Fu‐Jun

doi:10.4088/jcp.17m11599

Cited by 10 publications

(11 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For patients that did not attend medical homes, rural patients had a higher number of monthly specialty mental health visits, higher medication adherence, and less inpatient hospitalizations than urban patients (Kilany et al, 2018). In a large study in China, with 1,365 participants, Hou et al (2018) compared rural and urban community dwelling patients with regards to antipsychotic-free status. The proportion of antipsychotic-free patients was significantly higher in the rural area than in the urban area (35.4% vs 17.5%, respectively).…”

Section: Resultsmentioning

confidence: 99%

“…This finding does not necessarily mean that prognosis of schizophrenia is worse in rural areas; rather, it may be better perceived as the result of inadequate access to services and treatments by patients in rural areas. Moreover, the proportion of patients that did not receive antipsychotic treatment was higher in rural areas than in urban areas in China (Hou et al, 2018; Wei et al, 2020). It seems that the lack of mental health resources in rural areas may account for these treatment shortages.…”

Section: Discussionmentioning

confidence: 99%

“…Regarding treatment studies, as already mentioned, the Danish study found that the lower the degree of urbanicity the higher the risk of treatment resistant schizophrenia (Wimberley et al, 2016). Moreover, studies from China reported less antipsychotic use by rural patients with psychotic disorders (Hou et al, 2018; Wei et al, 2020), as well as less use of antipsychotic polypharmacy and clozapine (Hou et al, 2019). Inadequate mental health resources in rural areas and patients’ discrimination were accounted for the observed differences.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Research on psychotic disorders in rural areas: Recent advances and ongoing challenges

Peritogiannis¹,

Samakouri

2021

Int J Soc Psychiatry

View full text Add to dashboard Cite

Background: Research on patients with chronic psychotic disorders in rural areas is scarce. Those patients may not receive adequate mental health care. Mental health disparities among rural and urban areas have been recognized. Aims: This review aims to present the most recent research on psychotic disorders in rural areas. Method: We conducted a search in the PubMed and Scopus databases. The search involved articles published over the last decade (2011–2020). All types of research design were included, if studies had used a controlled group of urban patients and reported on the differences among rural/urban residents with psychotic disorders. The focus of the review was on outcome and treatment. Results: A total of 12 studies were included in this review. Most have been conducted in China or India. Reports from Western countries are rare. Outcome studies showed that employment rates are significantly higher in rural patients, as well as rates of marriage in women. It is not clear what is the impact of those outcomes on patients’ lives. The finding of lower cost of psychotic disorders in some rural areas, should be viewed with scepticism. Studies on treatment aspects suggested that rural patients were less likely to receive antipsychotics, antipsychotic combination or clozapine. Those results were attributed to limited access to specialized treatment. When rural patients receive specialized community care they seem to have better outcomes than urban patients. Conclusion: There is an ongoing, but still scarce research on patients with chronic psychotic disorders in rural areas. Researchers pointed out the impact of socioeconomic inequalities on outcome and treatment, and stressed the importance of minimizing mental health disparities. These findings may have potential implications for future research; for the introduction of accessible, locally based mental health services in rural areas; and for political initiatives that would address poverty and social inequalities.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Research on psychotic disorders in rural areas: Recent advances and ongoing challenges

Peritogiannis¹,

Samakouri

2021

Int J Soc Psychiatry

View full text Add to dashboard Cite

show abstract

“…The urban population received food from state grain stores, showing how urbanicity can affect resource access [31]. Another Chinese study showed that patients in rural compared to urban areas were less likely to take antipsychotics (35.4 vs. 17.5%) [32]. Lower education, living alone and number of admissions were predictors of not taking antipsychotics in urban areas, whereas female sex, low BMI, higher positive symptoms, lower anxiety and insight emerged as predictors in rural areas.…”

Section: Resultsmentioning

confidence: 99%

“…This review shows that urban environments do not increase the risk for psychosis by default, but that their effects are conditional on multiple factors. For instance, city living can offer benefits, like access to healthcare or resources, especially in less developed countries [31,32]. However, it is also characterized by lack of green space and high-intensity social encounters that might be particularly stressful for individuals with an increased liability for psychosis [36 ▪▪ ,39].…”

Section: Discussionmentioning

confidence: 99%

Psychosis and urbanicity

Fett

Lemmers-Jansen

Krabbendam

2019

Current Opinion in Psychiatry

View full text Add to dashboard Cite

Purpose of review Epidemiological studies associate city living with an elevated psychosis risk. Urban (social/economic) stress and exposure to environmental toxins, pollution or disease agents have been proposed to underlie this association. This review provides an update on the recent evidence (May 2017 – November 2018). Recent findings Of 647 screened studies, 17 on: urbanicity–psychosis associations in worldwide high, middle and low-income countries; explanatory mechanisms, including nature exposure, social and economic stressors and genetic risk; urbanicity effects on the brain and coping; and urbanicity and resources, were included. The reviewed evidence revealed complex patterns of urbanicity–psychosis associations with considerable international variation within Europe and between low, middle and high-income countries worldwide. Social and economic stressors (e.g. migration, ethnic density and economic deprivation), nature exposure and access to resources could only explain part of the urbanicity effects. Risk factors differed between countries and between affective and non-affective psychosis. Summary Urbanicity–psychosis associations are heterogeneous and driven by multiple risk and protective factors that seem to act differently in different ethnic groups and countries. Interdisciplinary research combining approaches, for example from experimental neuroscience and epidemiology, are needed to unravel specific urban mechanisms that increase or decrease psychosis risk.

show abstract

Urbanicity and psychotic experiences: Social adversities, isolation and exposure to natural environments predict psychosis

Beyer,

Brick,

Kühn

2024

Journal of Environmental Psychology

View full text Add to dashboard Cite

Antipsychotic-Free Status in Community-Dwelling Patients With Schizophrenia in China

Cited by 10 publications

References 41 publications

Research on psychotic disorders in rural areas: Recent advances and ongoing challenges

Research on psychotic disorders in rural areas: Recent advances and ongoing challenges

Psychosis and urbanicity

Urbanicity and psychotic experiences: Social adversities, isolation and exposure to natural environments predict psychosis

Contact Info

Product

Resources

About