Antiretroviral Treatment in Older Patients

Guaraldi, Giovanni; Gomes, André; Silva, Ana Rita

doi:10.1007/978-3-319-20131-3_10

Cited by 1 publication

(1 citation statement)

References 80 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Based on the presence of comorbidities, polypharmacy, and pharmacokinetic and pharmacodynamic alterations associated with age, Guaraldi [ 81 ] further expanded considerations in the choice of antiretroviral drug for these patients, with an emphasis on integrase inhibitors [ 82 ], owing to their tolerability, low toxicity, and low number of drug-drug interactions. However, given that multiple treatment options are available, treatment should be prescribed on an individual basis, informed by underlying resistance, comorbidities, and patient and provider preference.…”

Section: Clinical Considerations For the Care Of Older Hiv-infectementioning

confidence: 99%

Aging in HIV-Infected Subjects: A New Scenario and a New View

Negredo

Back

Blanco

et al. 2017

BioMed Research International

Self Cite

View full text Add to dashboard Cite

The prevalence of HIV-infected people aged 50 years or older is increasing rapidly; the proportion will increase from 28% to 73% in 2030. In addition, HIV-infected individuals may be more vulnerable to age-related condition. There is growing evidence that the prevalence of comorbidities and other age-related conditions (geriatric syndromes, functional or neurocognitive/mental problems, polypharmacy, and social difficulties) is higher in the HIV-infected population than in their uninfected counterparts. However, despite the potential impact of this situation on health care, little information exists about the optimal clinical management of older HIV-infected people. Here we examine the age-related conditions in older HIV-infected persons and address clinical management according to author expertise and published literature. Our aim is to advance the debate about the most appropriate management of this population, including less well-studied aspects, such as frequency of screening for psychological/mental and social and functional capabilities.

show abstract

Section: Clinical Considerations For the Care Of Older Hiv-infectementioning

confidence: 99%