Antiseptic barrier caps in central line-associated bloodstream infections: A systematic review and meta-analysis

Antiseptic barrier caps to prevent central line-associated bloodstream infections: A systematic review and meta-analysis

“…Our analysis is a comprehensive update of previous meta-analyses, which showed a CLABSI rate reduction of 0.43-0.60, which is in line with the rate ratio of 0.65 currently found in this study. 19,26,35 To date, only one small pilot study showed an increased infection rate with the use of ABCs, but, this concerned a non-significant trend most probably resulted from underpowering. 33 Taken together, the overall trend is in favor of the ABCs, despite the low quality of the majority of the articles.…”

“…The time-saving feature is highly appreciated by healthcare professionals, resulting in high compliance with cap use. 19 Implementation of these caps could provide a considerable help to prevent CLABSIs in clinical practice, as was described in a relative recent meta-analysis. 19…”

“…19 Implementation of these caps could provide a considerable help to prevent CLABSIs in clinical practice, as was described in a relative recent meta-analysis. 19…”

Engineering Photo-Crosslinked Antimicrobial Coating to Tackle Catheter-Associated Infections In Vivo

“…Urinary and intravascular catheters are two of the most used invasive medical devices; however, microbial colonization of catheter surfaces is responsible for most healthcare-associated infections. Consequently, in intensive care units, urinary and bloodstream infections are catheter-associated in 96.7% and 43.3% of the cases, respectively. − Central line-associated bloodstream infections (CLABSIs) often prove to be fatal, whereas catheter-associated urinary tract infections (CAUTIs) exhibit recurrence with serious deterioration in the quality of life, pain and discomfort, disruption of daily activities, and increased healthcare costs. , Currently available treatment options include long-term antibiotic prophylaxis. , However, several studies have asserted the role of biofilms in the establishment of catheter-associated infections . Such notorious biofilms render antibiotics ineffective .…”

“…7,8 Currently available treatment options include long-term antibiotic prophylaxis. 9,10 However, several studies have asserted the role of biofilms in the establishment of catheter-associated infections. 11 Such notorious biofilms render antibiotics ineffective.…”