Antiseptic drugs and disinfectants

Antiseptic drugs and disinfectants with experience of the second year of COVID-19 pandemic-related side effects

“…Considering all disinfectants, aldehydes have a special status as they have the ability to pose occupational hazards even at very low concentrations in air ( Lachenmeier, 2014 [R]; Lachenmeier, 2015 [R]; Lachenmeier, 2016 [R]; Lachenmeier, 2017 [R]; Lachenmeier, 2018 [R]; Lachenmeier, 2019 [R]; Lachenmeier, 2020 [R]; Lachenmeier, 2021 [R]).…”

“…Drug formulations : Chlorhexidine is used extensively in oral hygiene for preventing dental plaque and treating infections of the mouth, but can cause staining of the teeth and oral mucosa and adversely affect taste while rarely causing pain ( Lachenmeier, 2014 [R]; Lachenmeier, 2015 [R]; Lachenmeier, 2016 [R]; Lachenmeier, 2017 [R]; Lachenmeier, 2018 [R]; Lachenmeier, 2019 [R]; Lachenmeier, 2020 [R]). In a 3-month trial, chlorhexidine-based toothpaste (0.12%, twice daily brushing, n = 20) was associated with burning sensation in two patients and one patient had severe upper palatal tooth staining ( Cosola et al, 2021 ) [c].…”

Antiseptic drugs and disinfectants with special scrutiny of COVID-19 pandemic related side effects

“…Considering all disinfectants, aldehydes have a special status as they have the ability to pose occupational hazards even at very low concentrations in air ( Lachenmeier, 2014 [R]; Lachenmeier, 2015 [R]; Lachenmeier, 2016 [R]; Lachenmeier, 2017 [R]; Lachenmeier, 2018 [R]; Lachenmeier, 2019 [R]; Lachenmeier, 2020 [R]).…”

“…Polyhexamethylene guanidine (PHMG) has been used as an antiseptic, especially for the suppression of hospital infection in the Russian Federation and as a disinfectant for sterilization of household humidifiers in Korea ( Lachenmeier, 2014 [R]; Lachenmeier, 2015 [R]; Lachenmeier, 2016 [R]; Lachenmeier, 2017 [R]; Lachenmeier, 2018 [R]; Lachenmeier, 2019 [R]; Lachenmeier, 2020 ) [R]).…”

“…Sodium hypochlorite is used to irrigate root canals in dentistry and can cause many adverse reactions ( Lachenmeier, 2014 [R]; Lachenmeier, 2015 [R]; Lachenmeier, 2016 [R]; Lachenmeier, 2017 [R]; Lachenmeier, 2018 [R]; Lachenmeier, 2019 [R]; Lachenmeier, 2020 [R]). The occurrence of hypochlorite injuries during endodontic treatment, typically leading to localized or widespread tissue necrosis, is relatively rare but key to the successful treatment is an early identification of the condition ( Shetty, Al-Bayati, et al, 2020 ) [R].…”