65 agonists (e.g., clonidine) to block the release of acetyl-Other approaches to OP antidotes have dealt with choline from presynaptic nerve terminals (Buccafusco, changes in the heteroaromatic ring system in order to
65 agonists (e.g., clonidine) to block the release of acetyl-Other approaches to OP antidotes have dealt with choline from presynaptic nerve terminals (Buccafusco, changes in the heteroaromatic ring system in order to
Die Umsetzung von Trimethyl‐skatyl‐ammonium‐methylsulfat (XII) mit N‐Phenacyl‐pyridinium‐ oder ‐isochinolinium‐Salzen führt im alkalischen Medium zu den entsprechenden Skatyl‐Derivaten (z. B. XIII), die mit Alkali leicht zu N‐[β‐(Indolyl‐(3))‐äthyl]‐pyridinium‐ (I) bzw. ‐isochinolinium‐Salzen (III) hydrolytisch gespalten werden können.
Catalytic hydrogenation of pyridinium derivative for the preparation of analgesic Fentanyl, (N‐(l‐phenethyl‐4‐piperidyl)‐propionanilide) is reported. This constitutes a novel synthesis for the analogs of Fentanyl type compounds.
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