Antitumor, Analgesic and Anti-inflammatory Activities of Glochidion multiloculare (Rottler ex Willd) Voigt

Kabir, Selina; Zahan, Ronok; Chowdhury, A. M. Sarwaruddin; Haque, Mohammad Rashedul; Rashid, Mohammad A.

doi:10.3329/bpj.v18i2.24313

Cited by 5 publications

(3 citation statements)

References 26 publications

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“…[38] Historically, numerous Phyllanthus species have been utilized for treating various ailments such as hemorrhoids, diarrhea, dysentery, anemia, jaundice, indigestion, sleeplessness, and certain species have diuretic properties. [39] Glochidion puberum is employed in Chinese traditional medicine to address conditions such as dysentery, jaundice, abnormal uterine bleeding, the common cold, throat discomfort, tooth pain, as well as skin abscesses, boils, and rheumatic joint pain.…”

Section: Patimentioning

confidence: 99%

Sindhu Prakrit Unveils the Enigma: Revealing the origins of Ayurveda

Muhammad

2023

Preprint

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The paper analyzes some specific iconographic Indus seals. The readings of the text exhibit a remarkable correlation between the text and the iconography of the seals. These seals signify not only the diseases and their symptoms but also the medicinal plants used in their treatment. The spelling rules of the alphabet have been followed meticulously, indicating the importance attached to the accuracy of the information provided in these seals.The iconographic Indus seals provide valuable evidence of the earliest documentation of Ayurveda. These seals signify the knowledge and importance attached to healthcare in the ancient Indus Valley Civilization, highlighting the holistic approach towards medicine and healthcare prevalent during that era. This paper sheds light on the specific function of these seals in indicating diseases, symptoms, and medicines, highlighting the intricate relationship between the script and iconography on the seals. The evidence presented in this paper supports the notion that the Indus seals constitute a valuable resource for the study of the early history of medicine and the origins of Ayurveda.

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Section: Patimentioning

confidence: 99%

Sindhu Prakrit Unveils the Enigma: Revealing the origins of Ayurveda

Muhammad

2023

Preprint

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“…In Chinese traditional medicine Glochidion puberum is used in dysentery, jaundice, leukorrhagia, common cold, sore throat, toothache, carbuncle, furuncle, rheumatic arthralgia (Fenglin et al, 2004). Recent investigation showed that Glochidion multilculare possess antitumor, analgesic and anti-inflamatory potential (Kabir et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Triterpenoids Isolated from Stem Bark of Glochidion lanceolarium (Roxb.), Voigt

et al. 2021

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This paper presents the chemical investigation of the stem barks of Glochidion lanceolarium (Roxb.) Voigt, Euphorbiaceae. Classic phytochemical investigation of organic extracts of the aerial parts of Glochidion lanceolarium together with spectroscopic methods led to the isolation and characterization of three triterpenes, namely Epilupeol (1) Glochidonol (2), Glochidone (3). Journal of Science Foundation, January 2020;18(1):13-18

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“…According to the estimates of the WHO, more than 80% of people in developing countries depend on traditional medicine for their primary health needs (Kabir et al, 2015). The practice of herbal medicine is common in rural *Corresponding author.…”

Section: Introductionmentioning

confidence: 99%

Investigation of biological activities of Jasminum matthewii

Sharmin¹,

Rahman²,

Tahia³

2017

Afr. J. Pharm. Pharmacol.

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The crude methanol extract of leaves of Jasminum matthewii as well as its hexane, carbon tetrachloride, chloroform and aqueous soluble partitionates were subjected to screening for antioxidant, cytotoxic, thrombolytic, membrane stabilizing, antimicrobial, analgesic, anti-diarrheal and central nervous system depressant activity assays. The antioxidant potential was evaluated in terms of total phenolic content and free radical scavenging activity using butylated hydroxytolune (BHT) and ascorbic acid as standards. Among the test samples of J. matthewii, the highest free radical scavenging activity was demonstrated by the aqueous soluble fraction (IC 50 = 41.55±0.51 µg/ml), whereas in case of brine shrimp lethality bioassay, the hexane soluble fraction revealed the highest cytotoxic activity with LC 50 value 0.19±0.32 μg/ml. In thrombolytic activity assay, the aqueous soluble fraction of J. matthewii extractives showed 62.29±0.29% of clot lysis, whereas standard streptokinase demonstrated 66.77% clot lysis. Among the test samples, the crude methanol extract inhibited 70.15±0.39% haemolysis of red blood cells induced by hypotonic solution. In case of heat-induced condition, the aqueous soluble fraction demonstrated 25.25±0.31% inhibition of haemolysis of red blood cells. None of the test samples revealed any zone of inhibition in disc diffusion assay. In peripheral analgesic activity assay, the crude methanol extract of J. matthewii demonstrated 51.02% inhibition of writhing at a dose of 400 mg/kg body weight dose compared to 74.49% inhibition by standard diclofenac sodium. In anti-diarrheal activity assay, the methanolic crude extract reduced diarrheal feces by 89.00±0.15% at 400 mg/kg dose. J. matthewii extractives potentiated phenobarbitone sodium-induced sleeping time in a dose dependent manner.

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Antitumor, Analgesic and Anti-inflammatory Activities of Glochidion multiloculare (Rottler ex Willd) Voigt

Cited by 5 publications

References 26 publications

Sindhu Prakrit Unveils the Enigma: Revealing the origins of Ayurveda

Sindhu Prakrit Unveils the Enigma: Revealing the origins of Ayurveda

Triterpenoids Isolated from Stem Bark of Glochidion lanceolarium (Roxb.), Voigt

Investigation of biological activities of Jasminum matthewii

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