Antiviral activity and cytotoxicity of the lipophilic extracts of various edible plants and their fatty acids

Orhan, İlkay Erdoğan; Deliorman‐Orhan, Didem; Özçelık, Berrın

doi:10.1016/j.foodchem.2009.01.024

Cited by 81 publications

(55 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Besides, hexadecatrienoic acid has also been reported to present a moderate antiviral activity (Guang-Zhou et al, 2004). The antiviral activity of hexane extract could be explained by the presence of the hexadecanoid acid (palmitic acid) that have been proposed to possess antibacterial and antiviral activities in some cases (Yff et al 2002;Orhan et al 2009). …”

Section: Pressurized Liquid Extraction Is An Emerging Extraction Techmentioning

confidence: 99%

“…The GC-MS analysis of Dunaliella hexane and ethanol extracts allowed identification of several compounds with antimicrobial and antiviral effects, such as: β-ionone, neophytadiene, phytol, hexadecanoic acid and 9, 12, 15-octadecatrienoic acid (Aranzaldi et al, 1999;Yff et al, 2002;Orhan et al, 2009;Santoyo et al, 2010a).…”

Section: Pressurized Liquid Extraction Is An Emerging Extraction Techmentioning

confidence: 99%

See 1 more Smart Citation

Antiviral compounds obtained from microalgae commonly used as carotenoid sources

et al. 2011

View full text Add to dashboard Cite

Pressurized liquid extraction (PLE), an environmentally friendly technique, has been used to obtain antiviral compounds from microalgae commonly used as carotenoids sources: Haematococcus pluvialis and Dunaliella salina. The antiviral properties of PLE extracts (hexane, ethanol and water) were evaluated against herpes simplex virus type 1 (HSV-1) at different stages during viral infection. Pre-treatment of Vero cells with 75 g mL -1 of H. pluvialis ethanol extract inhibited virus infection by approx. 85%, whereas the same concentration of water and hexane extracts reduced the virus infectivity 75% and 50% respectively. D. salina extracts were less effective than H. pluvialis extracts and presented a different behaviour, since water and ethanol extracts produced a similar virus inhibition (65%). Moreover, H. pluvialis ethanol extract was also the most effective against HSV-1 intracellular replication.The antiviral activity of water PLE extracts was found to correlate with polysaccharides, since the polysaccharide-rich fraction isolated from these extracts showed higher antiviral activity than the original water extracts. A GC-MS characterization of the H.pluvialis ethanol extract showed the antiviral activity of this extract could be partially related with the presence of short chain fatty acids, although other compounds could be involved in this activity; meanwhile, in the case of D. salina ethanol extract other compounds seemed to be implied, such as: β-ionone, neophytadiene, phytol, palmitic acid and α-linolenic acid.

show abstract

Section: Pressurized Liquid Extraction Is An Emerging Extraction Techmentioning

confidence: 99%

Section: Pressurized Liquid Extraction Is An Emerging Extraction Techmentioning

confidence: 99%

Antiviral compounds obtained from microalgae commonly used as carotenoid sources

et al. 2011

View full text Add to dashboard Cite

show abstract

“…Antimicrobial, antiviral and antifeedant and cytotoxic properties of various extracts of this plant have been reported (Kutas & Nadasy, 2005;Akçin et al, 2006;Orhan et al, 2009;Turkoglu et al, 2010). Previous phytochemical investigations on this plant revealed the presence of cloredan and neocloredan diterpenes in the aerial parts, and β-pinene and germacrene-D as the major components of the essential oils (Hernandez et al, 1980;Camps et al, 1984Camps et al, , 1987Boneva et al, 1990;Baser et al, 1999;Azizan et al, 2002;Velasco-Negueruela et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

Essential oil composition and isolation of freeradical-scavenging phenolic glycosides from the aerial parts of Ajuga chamaepitys growing in Iran

Delazar

Delnavazi

Yassa

et al. 2012

Rev. bras. farmacogn.

View full text Add to dashboard Cite

Abstract:From the methanolic extract of the aerial parts of Ajuga chamaepitys (L.) Schreb., Lamiaceae, one of the Iranian medicinal plants, the phenylethanoid glycoside, acteoside, and two flavone glycosides, chrysoeriol 7-Oglucopyranoside (3'-methoxy-luteolin 7-O-glucopyranoside) and apigenin 7-Orhamnopyranoside, were isolated by a combination of solid-phase extraction (SPE) and preparative reversed-phase high-performance liquid chromatography (prep-RP-HPLC) methods. Structures of the isolated compounds were elucidated by spectroscopic means. The free-radical-scavenging properties of the extracts, fractions and isolated compounds were determined by the 2,2-diphenyl-1-picryl-hydrazyl (DPPH) assay. While among the extracts, the MeOH extract showed the highest level of free-radical-scavenging activity (RC50 1.15 × 10 -¹ mg/mL), chrysoeriol 7-O-glucopyranoside was the most active (RC50 3.00 × 10 -³ mg/mL) among the isolated compounds. The GC-MS and the GC-FID analyses revealed α-pinene (23.66%), β-pinene (9.33%), 1-octen-3-ol (9.72%), β-phellandrene (8.70%) and germacrene-D (7.92%) as the major components of the essential oils derived from the aerial parts of this plant. The presence of phenolic glycosides and the α-and β-pinene-rich essential oils in A. chamaepitys may provide some rationale for the traditional medicinal uses of this species in Iran.

show abstract

“…recently, cerotic and palmitic acids were claimed to be the major MUFAs in the oil of Anthemis tinctoria var. tinctoria and A. austriaca 25 . In a previous study, palmitic acid and α-linolenic acid were reported to be the main constituents of A. triumfetti 11 .…”

Section: Resultsmentioning

confidence: 99%

Fatty Acid Profile of Four Anthemis Species Growing in İzmi̇r, Turkey

Taştan¹,

Gönenç²,

Tüzün³

et al. 2017

NWSA

View full text Add to dashboard Cite

show abstract

Antiviral activity and cytotoxicity of the lipophilic extracts of various edible plants and their fatty acids

Cited by 81 publications

References 8 publications

Antiviral compounds obtained from microalgae commonly used as carotenoid sources

Antiviral compounds obtained from microalgae commonly used as carotenoid sources

Essential oil composition and isolation of freeradical-scavenging phenolic glycosides from the aerial parts of Ajuga chamaepitys growing in Iran

Fatty Acid Profile of Four Anthemis Species Growing in İzmi̇r, Turkey

Contact Info

Product

Resources

About