Antiviral activity of five filamentous cyanobacteria against coxsackievirus B3 and rotavirus

Docking and in silico toxicity assessment of Arthrospira compounds as potential antiviral agents against SARS-CoV-2

“…In the work of Chen et al 2016, Arthrospira extract was capable of inhibiting in vitro influenza viral replication and plaque formation (Table 1), by targeting hemagglutinin, an influenza virus surface glycoprotein. Abdo et al (2012), El-Baz et al (2013, Deyab et al (2020), and Hetta et al (2014) focused on A. platensis antiviral effect on adenovirus and Coxsackievirus (CV). Most of them evaluate Arthrospira methanol extract activity on Hep-2 cell in vitro model.…”

“…Most of them evaluate Arthrospira methanol extract activity on Hep-2 cell in vitro model. In all cases, Arthrospira appears as a good antiviral agent: reducing virus titer from 50% and preventing virus from attaching to host cell receptor when used as pre-treatment with TI(CVB3) = 30 and TI(RV) = 45 (Deyab et al 2020). Efficiency of methanolic extract is attributed to the presence of polar compounds binding to viral capsid.…”

Docking and in silico toxicity assessment of Arthrospira compounds as potential antiviral agents against SARS-CoV-2

“…Most of them evaluate Arthrospira methanol extract activity on Hep 2 cell in vitro model. In all cases, Arthrospira appears as a good antiviral agent: reducing virus titer from 50%, preventing virus attach to host cell receptor when used as pre-treatment with TI(CVB3) = 30 and TI(RV)= 45 (Deyab et al 2020). E ciency of methanolic extract is attributed to the presence of polar compounds binding to viral capsid.…”

Mass production of Arthrospira platensis on the livestock manure for use as a protein source in animal feed

“…Using of algae as a food for both humans and animals is one of these solutions because this valuable group of organisms contains a high percentage of proteins, carbohydrates, and lipids in addition to varieties of mineral and vitamins (Renaud et al, 1999;Pulz and Gross, 2004;Becker, 2007;Abdel-Hamid et al, 2015a;Mofeed et al, 2019). Algae became a powerful raw material for many applications in our life not only as food and feed (Becker, 2004;Pulz and Gross, 2004;Abdel-Hamid et al, 2016) but also in therapeutic pharmaceuticals (Bansemir et al, 2006;Madkour et al, 2012aMadkour et al, , 2019Abdel-Aal et al, 2015;Deyab et al, 2020), nutritional and cosmetic industries (Pulz and Gross, 2004), in addition to its applications in the production of biofuel (Abdel-Aal, 2013; Abdel-Aal and Mofeed, 2015;Abdel-Hamid et al, 2015b;Abdel-Hamid et al, 2019), bioplastic and purification of waste or even as a biomarker for different types of pollutants in aquatic habitats (Shaaban-Desouki et al, 2004;Ward et al, 2012;Mofeed and Mosleh, 2013;Abdel-Hamid et al, 2014, 2017Mofeed, 2017;Abdel Gawad and Abdel-Aal, 2018).…”

“…Arthrospira platensis Gomont 1892 is the most applicable algae throughout the recent decades due to the fact that in terms of the chemical composition it is a very rich food source of both macro-and micronutrients including high-quality protein content up to 70% of the dry weight, essential fats (e.g., gamma-linolenic and oleic acids), essential amino acids, vitamins (e.g., B12), β-carotene, lipids and polysaccharides with a distinctive high content of calcium, iron, phosphorous, minerals, sulfated and phycocyanin, besides its antioxidant capacity (Phang et al, 2000;Babadzhanov et al, 2004;Abdel-Daim et al, 2015, 2020Mofeed, 2019). Moreover, A. platensis showed neither chronic nor any acute toxicity or even harmful effects, making it safe to use as part of diets for human food and as a dietary supplement of poultry and fish feed production as a non-conventional high protein source (Habib et al, 2008;El-Sheekh et al, 2014).…”