Antiviral activity of panamanian plant extracts

Abstract

These extracts had direct virucidal activity as well as intracellular antiviral activity against both DNA and RNA viruses. Antiviral activity was achieved with extract concentrations significantly lower than those necessary to produce cytotoxic effects. Additionally, extracts were less toxic to normal cells than to the tumour cells tested.

Inhibitory effects of various ayurvedic and Panamanian medicinal plants on the infection of herpes simplex virus‐1 in vitro and in vivo

“…As regards Panamanian tropical plants, Ouratea fucens and Trichilia cipo extracts were recently reported to have direct virucidal activity as well as intracellular antiviral activity against DNA and RNA viruses (Roming et al, 1992). Our present experiments provide further evidence for antiviral properties of some Panamanian plant extracts.…”

“…Many studies have been conducted on the evaluation of medicinal plants for their direct inhibitory actions against the growth of bacteria, fungi, parasites, viruses etc. (Hattori et af., 1986;Namba et af., 1981Namba et af., , 1982Kiuchi et al, 1989a, b;Ali etaf., 1991;Chang and Yeung, 1988;Che, 1991;Roming et al, 1992). Although most of the infectious diseases can be controlled by antibiotics, synthetic pharmaceuticals and vaccines, a great number of plants in the world and their countless ingredients are still quite interesting resources for the development of medicines.…”

Chemical constituents from Ouratea floribunda: complete¹H and 13C NMR assignments of atranorin and its new acetyl derivative

“…Some species of this genus have been shown to possess antiviral (Ouratea lucens, from Panama) 2 , antimicrobial (O. parviflora, from Brazil) 3 as well as pain relief (O. reticulata, from Guinea) activities 4 . The species O. spectabilis, from Brazil, has been reported to be used in folk medicine for the treatment of rheumatic and gastric distress.…”

Effect of extracts of Trichilia silvatica C. DC., on development and reproduction parameters of Spodoptera frugiperda (J. E. Smith) (Lepidoptera: Noctuidae)

“…The limonoids of Meliaceae are very complex with a high degree of oxidetion and rearrangement exhibited in the parent limonoid structure. Compounds belonging to this group express a wide range of biological activities like insecticidal deterrence, insect antifeedant and growth regulating capacity on insects (Champagne et al, 1989;Kubo and Klocke, 1982;Mikolajczak and Reed, 1987;Mikolajczak et al, 1989;Nakatani et al, 1981;Simmonds et al, 2001;Xie et al, 1994) as well as antiviral and analgesic, and several other pharmacological effects on humans (Romin et al, 1992;Vaz et al, 1997).…”