Antiviral therapy for genital herpes for prevention of HIV transmission

Ng, Brian; Rutherford, George W; Broad, Angela L; Moore, David

doi:10.1002/14651858.cd006492.pub2

Cited by 2 publications

(1 citation statement)

References 44 publications

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“…Hence, the early diagnosis of HSV-2 and early treatment can prevent possible transmission of the virus to others and lower the risk of acquiring HIV in those patients. For individuals who are negative for HIV and HSV that are engaging in a sexual relationship with a partner who is positive for both HSV and HIV, prophylactic treatment with antiviral medications can reduce the risk of contracting HSV and HIV infections [10]. In patients with HIV and AIDS, studies suggest that an aggressive treatment route with HAART therapy along with HSV antiviral medications can provide an improved survival benefit [5].…”

Section: Discussionmentioning

confidence: 99%

Herpes Virus Pseudotumor in a Patient with HIV Immunosuppression

York

Patel

Saikumar

2022

Case Reports in Obstetrics and Gynecology

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Background. In rare cases, HSV infections can present as pseudotumors that are often mistaken as malignancies in patients with an uncontrolled HIV infection. Herpes simplex virus type 2 (HSV-2) infection rates range from 60% to 90% in individuals coinfected with HIV. Case Presentation. A 48-year-old patient presented with a large fungating mass near her right inferior vulva with a hardness of surrounding tissues. The mass was 4 cm × 3 cm in size and was excised in the operating room. The pathology was negative for malignancy; however, it showed lymphoplasmacytic proliferation with immunostaining positive for HSV virus. Conclusion. Atypical HSV pseudotumors should be considered in the differential diagnosis for an immunosuppressed patient who presents with a genital mass lesion.

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Section: Discussionmentioning

confidence: 99%