SUMMARYFifty-three hospitalized elderly men with medical illness were diagnosed with major depressive disorder and followed up for a mean of 2.3 months. Documentation and management of the depression by medical housestaff during the followup period were examined. There was no note of depression in the medical records of 44% of depressed patients, and depression was on the active problem list of only 32%. Followup and management plans for the depression after discharge were documented in 29%. No form of treatment was prescribed for 44% of depressed patients. Outcomes were determined by psychiatric evaluation at the end of the followup period. Of the 33 patients still alive and evaluated at followup, 64% had persistent depression, 18% improved, and 18% were in complete remission. No baseline patient sociodemographic or health characteristic, including severity of depression, was significantly related to improvement. Likewise, neither extent of documentation nor treatment implemented by housestaff was a significant predictor of outcome. We conclude that serious clinical depression in medically ill older patients may persist for a considerable period after hospital discharge and neither detection nor current management strategies appear to have a major impact on outcome.KEY woms-Major depression, elderly, medically ill, hospital, treatment, outcome, documentation.Major depressive disorder is common among older medically ill hospitalized patients. Recent studies have demonstrated that the prevalence rate of this disorder in elderly hospitalized men may be 15 to 30 times as high as in community settings. The NIMH Epidemiologic Catchment Area studies a t five sites in the United States found rates of major depression in community-dwelling men age 65 or over averaged 0.4% (Weissman et al., 1988). Studies of hospitalized elderly male inpatients have found rates for major depressive disorder varying from 5% to 13%) (O'Riordan et al., 1989;Rapp et al., 1988a; Koenig etal., 1988a Koenig etal., , 1991. Despite this fact, very little is known about the epidemiology of serious depressive disorders in the medical setting, the detection and management of these disorders by medical physicians, or outcomes after hospital discharge. Part of the problem is that small samples have limited the number of major depressive disorders available for study, with cases ranging from 5 to 15 in most reports.Detection rates of depression have been reported as low as 9% by primary care physicians in older medical inpatients (Rapp et al., 1988b). Rates of antidepressant use in medical inpatients are in the range of 0.5-1.6% (Raft et al., 1975;Callies and