Anxiety and Depression in Cardiac Patients: Age Differences and Comparisons with the General Population

Hinz, Andreas; Kittel, Jörg; Karoff, Marthin; Daig, Isolde

doi:10.1159/000322796

Cited by 18 publications

(19 citation statements)

References 66 publications

(33 reference statements)

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“… 13 In addition, compared with the rank order of the probability rates in the “high” class, the occurrence rates for the psychological symptoms in the “intermediate” class were relatively low. This finding is consistent with population-based studies, 49 – 51 as well as with a previous study of oncology patients, 42 that found that older patients tend to report lower occurrence rates for depression and anxiety.…”

Section: Discussionsupporting

confidence: 92%

Distinct symptom experiences in subgroups of patients with COPD

Christensen¹,

Rustøen²,

Cooper³

et al. 2016

COPD

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BackgroundIn addition to their respiratory symptoms, patients with COPD experience multiple, co-occurring symptoms.ObjectivesThe aims of this study were to identify subgroups of COPD patients based on their distinct experiences with 14 symptoms and to determine how these subgroups differed in demographic and clinical characteristics and disease-specific quality of life.Patients and methodsPatients with moderate, severe, and very severe COPD (n=267) completed a number of self-report questionnaires. Latent class analysis was used to identify subgroups of patients with distinct symptom experiences based on the occurrence of self-reported symptoms using the Memorial Symptom Assessment Scale.ResultsBased on the probability of occurrence of a number of physical and psychological symptoms, three subgroups of patients (ie, latent classes) were identified and named “high”, “intermediate”, and “low”. Across the three latent classes, the pairwise comparisons for the classification of airflow limitation in COPD were not significantly different, which suggests that measurements of respiratory function are not associated with COPD patients’ symptom burden and their specific needs for symptom management. While patients in both the “high” and “intermediate” classes had high occurrence rates for respiratory symptoms, patients in the “high” class had the highest occurrence rates for psychological symptoms. Compared with the “intermediate” class, patients in the “high” class were younger, more likely to be women, had significantly more acute exacerbations in the past year, and reported significantly worse disease-specific quality of life scores.ConclusionThese findings suggest that subgroups of COPD patients with distinct symptom experiences can be identified. Patients with a higher symptom burden warrant more detailed assessments and may have therapeutic needs that would not be identified using current classifications based only on respiratory function.

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Section: Discussionsupporting

confidence: 92%

Distinct symptom experiences in subgroups of patients with COPD

Christensen¹,

Rustøen²,

Cooper³

et al. 2016

COPD

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“…This is consistent with research in a variety of chronic illnesses that indicates that younger age is associated with more psychological distress (Cassileth et al, 1984; Hinz et al, 2011; Hughson et al, 1988; Jamison et al, 1978; Schrag et al, 2003; Starkstein et al, 1989; Vinokur et al, 1989) and worse quality of life (Ganz et al, 1992; Schrag et al, 2003). Most studies have been cross-sectional and have not focused on the association of age with patient report of physical symptoms such as breathlessness.…”

Section: Introductionsupporting

confidence: 90%

The impact of age on outcomes in chronic obstructive pulmonary disease differs by relationship status

et al. 2013

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Alpha-1 antitrypsin deficiency (AATD) is a genetic condition that can lead to early-onset chronic obstructive pulmonary disease (COPD). The objective of this study was to examine the impact of age on psychological and clinical outcomes among individuals with AATD-associated COPD. 468 individuals with AATD-associated COPD (age 32 to 84 at baseline) completed questionnaires at baseline, 1- and 2-year follow-up. Age was examined as a predictor of depression, anxiety, health-related quality of life, and breathlessness at all three time points using linear mixed models. Age was associated with anxiety (b = −0.09, SE = 0.02, p < 0.001) and health-related quality of life (b = −0.29, SE = 0.09, p < 0.001). Age also had a statistically significant interaction with relationship status when predicting depression, health-related quality of life, and breathlessness. Among individuals who were single, younger age was associated with more symptoms of depression (b = −0.08, SE = 0.03, p < 0.01), worse health-related quality of life (b = −0.61, SE = 0.16, p < 0.001), and more breathlessness (b = −0.023, SE = 0.009, p < 0.01) throughout the two-year study. Age was not associated with these three outcomes among individuals who were married/part of an unmarried couple. Results suggest that individuals who develop a chronic illness at a young age, particularly those who are single, may be more likely to have worse psychological and clinical outcomes.

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“…One study [12] examined anxiety and depression following venous thromboembolism, reporting elevated levels of anxiety and depression symptoms in the first 1-4 weeks following the event. In patients with chronic cardiovascular disease, anxiety is reported to persist in 20-25 % of patients following an acute cardiac event [13], and especially younger cardiac patients experience impaired mental health [14].…”

Section: Introductionmentioning

confidence: 99%