Anxiety and mood disorder in young males with mitral valve prolapse

Abstract

This study explored the prevalence of panic disorder and other psychiatric disorders in young Han Chinese males with mitral valve prolapse (MVP). With the factors of age, sex, and ethnicity controlled, the specifi c role of MVP in panic disorder was analyzed. Methods: Subjects with chest pain aged between 18 and 25 years were assessed with the echocardiograph for MVP and the Chinese version of the Mini-International Neuropsychiatric Interview for panic disorder (n = 39). Results: Of the 39 participants, 35.9% met the diagnosis of anxiety disorder, 46.2% met at least one criterion of anxiety disorder, and 23.1% met the diagnostic criteria of major depressive disorder. There was no statistically signifi cant difference in the prevalence of panic disorder between one of the (8.3%) MVP patients, and two (7.4%) control participants. Conclusions: There is a high prevalence of psychiatric disorder, including anxiety disorder and major depressive disorder, in those who report pain symptoms, so that diagnosis and treatment of these patients is of great importance. In addition, individuals with MVP did not have an increased risk for panic disorder. Whether MVP may be a modifi er or mediating factor for panic disorder needs to be further assessed in a larger scale study.

The Association between Default-mode Network Functional Connectivity and Childhood Trauma on the Symptom Load in Male Adults with Methamphetamine Use Disorder

“…Each patient was initially interviewed and diagnosed by a board-certified psychiatrist and then screened by a research team member well trained in using the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5), criteria [24] and the Chinese version of the Mini International Neuropsychiatric Interview (MINI) [25]. The MINI has good reliability and has been widely used in clinical trials and epidemiological studies [26], and its interrater reliability in the Chinese version was approximately 0.75 in previous studies [27,28].…”

Are children with mitral valve prolapse more anxious?

“…[ 4 5 6 ] However, there are also studies supporting that MVP does not contribute to an increase in anxiety levels. [ 7 8 9 10 ] Furthermore, it is important to determine whether there is mitral regurgitation (MR) with MVP because it has been shown that posttraumatic stress disorder associated with anxiety and depression is more common in patients with organic-MR than in normal controls and simple MVP. [ 11 ]…”