Anxiety, Depression and Sleep Disturbances among Renal Disorders in Tertiary Care Center

Abstract

Depression is the most general psychiatric disease in patients with Chronic Kidney Disease (CKD). Depression exposed to affect mortality in end-stage renal disease patient. The main focus of this study was to measure the occurrence of painful symptoms among CKD patients. Co-morbid depression influences harmfully on the excellence of life in Chronic Kidney Disease patients. This study was done to calculate predominance of depression inpatient on hemodialysis (HD) using Patient Health Questionnaire-9, Hamilton Rating Scale for Depression-17 and International Classification of Disease-10 classification of mental and behavioural disorders. It was a cross-sectional study conducted from December 2019 till July 2020, in Nandhyala, Kurnool district region. Informed and written consent was taken. Patients undergoing hemodialysis at the Nandhyala, Kurnool district region for more than three months duration were involved in the study. Psychiatrists monitored Hamilton Rating scale for diagnosis and categorization of depression. Psychiatrists confirmed depression based on International Classification of Disease-10 scale. SPSS version.20 was used for statistical analysis. The study was done among 300 patients. Prevalence of depression was 234 using Patient Health Questionnaire-9 (PHQ-9)and 195 using Hamilton Rating scale (HAD-17)and 153 using International Classification of Disease -10 (ICD-10). Mean depression in females using PHQ-9 was 7±4.33 and in males was 11.04±5.90, and the Median age was 47.6 years. The most common symptom was fatigue among 246. There is a high occurrence of depression in patients with Chronic Kidney Disease (CKD) stage 5 on hemodialysis compared to the general population.

Global Prevalence of Depression in Chronic Kidney Disease: A Systematic Review and Meta-Analysis

“…Participants (3 studies) from AFR [30,58,70]; 4,295 (14 studies) from EUR [31,33,34,36,39,43,56,61,66,68,75,78,80,82]; 3,962 (17 studies) from AMR [22,23,24,25,26,29,32,35,38,45,53,55,62,65,67,69,77]; 679 (7 studies) from EMR [40,49,51,60,64,74,81]; 846 (7 studies) from SEAR [28,47,50,59,71,73,79], and 69,660 (13 studies) from the WPR. [27,37,41,42,44,46,48,52,54,57,63,72,76] Figure 2 shows the geographical distribution of the continents of the included studies.…”

“…The clinical diagnostic criteria included those of the DSM (20 studies, 2,028 participants) [23,26,27,28,32,34,35,42,46,49,56,60,66,67,70,72,73,74,76,78] ICD (5 studies, 69,954 participants) [25,37,47,71,79] SCID (15 studies, 1,435 participants)[22,33,39,40,43,48,51,53,54,56,57,59,61,65,82], and MINI (21 studies, 6,274 participants). [24,29,30,31,36,38,41,44,45,50,52,55,58,62,64,68,69,75,77,80,81] The sample size of the component studies ranged from 20 [70] to 67,866 [37] patients, with the proportion of women ranging from 0% [25] to 68% [74].…”

“…Patients and/or the public were not involved in the design, conduct, reporting, or dissemination plans of this research. participants (3 studies) from AFR [30,58,70]; 4,295 (14 studies) from EUR [31,33,34,36,39,43,56,61,66,68,75,78,80,82]; 3,962 (17 studies) from AMR [22,23,24,25,26,29,32,35,38,45,53,55,62,65,67,69,77]; 679 (7 studies) from EMR [40,49,51,60,64,74,81]; 846 (7 studies) from SEAR [28,47,50,59,71,73,79], and 69,660 (13 studies) from the WPR. [27,…”

“…The clinical diagnostic criteria included those of the DSM (20 studies, 2,028 participants)[23,26,27,28,32,34,35,42,46,49,56,60,66,67,70,72,73,74,76,78] ICD (5 studies, 69,954 participants)[25,37,47,71,79] SCID (15 studies, 1,435 participants)[22,33,39,40,43,48,51,53,54,56,57,59,61,65,82],24,29,30,31,36,38,41,44,45,50,...…”