Anxiety Disorders During Pregnancy

Goodman, Janice H.; Chenausky, Kerry L.; Freeman, Marlene P.

doi:10.4088/jcp.14r09035

Cited by 240 publications

(172 citation statements)

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“…Nearly 20%-40% of pregnancies are complicated by adverse intrauterine conditions, including maternal mental health disorders, diabetes, obesity, and preeclampsia (Ananth et al, 2013;Bennett et al, 2004;Dawson et al, 2015;DeSisto et al, 2014;Goodman et al, 2014;Rubertsson et al, 2014). These fetal exposures are significant risk factors for neuropsychiatric disease predisposition, in particular in male offspring.…”

Section: Resultsmentioning

confidence: 99%

The Placenta as a Mediator of Stress Effects on Neurodevelopmental Reprogramming

Bronson

Bale

2015

Neuropsychopharmacol

211

180

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Adversity experienced during gestation is a predictor of lifetime neuropsychiatric disease susceptibility. Specifically, maternal stress during pregnancy predisposes offspring to sex-biased neurodevelopmental disorders, including schizophrenia, attention deficit/hyperactivity disorder, and autism spectrum disorders. Animal models have demonstrated disease-relevant endophenotypes in prenatally stressed offspring and have provided unique insight into potential programmatic mechanisms. The placenta has a critical role in the deleterious and sex-specific effects of maternal stress and other fetal exposures on the developing brain. Stress-induced perturbations of the maternal milieu are conveyed to the embryo via the placenta, the maternal-fetal intermediary responsible for maintaining intrauterine homeostasis. Disruption of vital placental functions can have a significant impact on fetal development, including the brain, outcomes that are largely sex-specific. Here we review the novel involvement of the placenta in the transmission of the maternal adverse environment and effects on the developing brain.

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Section: Resultsmentioning

confidence: 99%

The Placenta as a Mediator of Stress Effects on Neurodevelopmental Reprogramming

Bronson

Bale

2015

Neuropsychopharmacol

211

180

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“…Up to 18.4 % of women develop depressive symptoms during pregnancy, and around 12.7 % of pregnant women suffer from major depression requiring treatment [135]. The figures for the prevalence of anxiety disorders in pregnancy range from 4.4 to 39 % [136]. Pregnancy-specific anxiety is very common; approximately 34 % of pregnant women are anxious about the impending birth, 32.4 % of women are afraid of perineal tears or an episiotomy, and 26.8 % are scared of the labor pains [137].…”

Section: Effects Of Stress Depression and Anxiety In Pregnancymentioning

confidence: 99%

Consequences and Possible Predictors of Health-damaging Behaviors and Mental Health Problems in Pregnancy – A Review

Ulrich

Petermann

2016

Geburtshilfe Frauenheilkd

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!In recent decades, the understanding of the short and longer term effects of health-damaging behaviors and mental health problems in pregnant women and the underlying mechanisms of these behaviors and illnesses has significantly increased. In contrast, little is known about the factors affecting individual pregnant women which contribute to health-damaging behaviors and mental illness. The aim of this paper was therefore to summarize the current state of research into the consequences of nicotine and alcohol consumption, malnutrition, excessive weight gain or obesity, and impaired mental health (depression and anxiety) during pregnancy. In addition, the characteristics of pregnant women which increase their risk of developing such behaviors or mental disorders are described. A better knowledge of these risks should make it easier for clinicians to identify cases at risk early on and put measures of support in place. A review of the literature has shown that certain characteristics of pregnant women (e.g. her relationship with her partner, a previous history of mental illness prior to pregnancy) are associated with various healthdamaging behaviors as well as with impaired mental health. Affected women often show an accumulated psychosocial stress which was already present prior to the pregnancy and which may persist even after the birth of the child. Zusammenfassung Consequences and Possible Predictors of Health-damaging Behaviors and Mental Health Problems in Pregnancy -A ReviewAuswirkungen und mögliche Prädiktoren gesundheitsschädigender Verhaltensweisen und psychischer Beeinträchtigungen in der Schwangerschaft -ein Überblick

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“…Postpartum anxiety has been assessed in some studies as one of the most common psychological disorders in this period [1][2][3] . There are few studies regarding postpartum anxiety, since anxiety and depression occur simultaneously, women with depression symptoms during postpartum period have clinically experienced anxiety symptoms; moreover, anxiety disorder without depression is also common among women 4 .…”

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confidence: 99%

“…Also, it is known that there is a relationship between severity of mother's psychological disorder and having problem in breast feeding 7 . Women with severe anxiety may have aggressive opinion to their child in the first 6 month after labor 3 . In a previous study in Iran, it was well known that the growth index was significantly lower in children whose mothers have severe anxiety compared to those without anxiety.…”

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confidence: 99%

The Relation Between Maternity Blues and Postpartum Anxiety Among Iranian Pregnant Women

Kariman¹,

Karimi²,

Shiadeh³

et al. 2016

Biosci., Biotech. Res. Asia

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Anxiety disorder is one of the most common psychological diseases in postpartum period. This study is designed to assess the relation between maternity blues and postpartum anxiety among Iranian pregnant women In this prospective study, 310 pregnant women (37-40 weeks of pregnancy) who fitted inclusion criteria and had informed consent were selected using convenience sampling method. Demographic and obstetric characteristics and Spiegelberger anxiety questionnaire was complete for each participant. In the first stage, 3-10 days after labor all cases were screened for maternity blues using Stein maternity blues questionnaire, then divided in to two groups with and without maternity blues. In the second stages, 4-6 weeks after labor the prevalence of postpartum anxiety was assessed using Spiegelberger questionnaire. There were significant relations between maternity blues and postpartum Trait anxiety (RR=6.8, CI= 3.6-12.5, P<0.001) and maternity blues and postpartum state anxiety (RR=7.5, CI= 4.1 -13.8, P<0.001). This study confirmed that the incidence of anxiety is more among women with maternity blues at 4-6 weeks postpartum. Given these findings, it is recommended to carefully follow mothers with maternity blues in order to identify women prone to progression of anxiety and their subsequent treatments.

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Anxiety Disorders During Pregnancy

Abstract: Additional research of higher methodological quality is required to more accurately determine prevalence, understand course, identify risk factors and outcomes, and determine effective treatments for anxiety disorders in pregnancy.

Cited by 240 publications

References 0 publications

The Placenta as a Mediator of Stress Effects on Neurodevelopmental Reprogramming

The Placenta as a Mediator of Stress Effects on Neurodevelopmental Reprogramming

Consequences and Possible Predictors of Health-damaging Behaviors and Mental Health Problems in Pregnancy – A Review

The Relation Between Maternity Blues and Postpartum Anxiety Among Iranian Pregnant Women

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