Anxiolytic effects of lavender oil inhalation on open-field behaviour in rats

Shaw, David; Annett, Judith; Doherty, Bernadette; Leslie, Julian C.

doi:10.1016/j.phymed.2007.03.007

Cited by 114 publications

(74 citation statements)

References 26 publications

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“…The increase in the number of crossing (exploratory activity) is a sign of intrinsic inhibition of anxiety induction and not an increase in locomotion since rearing which is a locomotion indicator in this test was reduced (Ngo Bum et al, 2009; Pitchaiah et al, 2008;Pollyanna and al., 2007). Reduction of defecation in mice treated with diazepam and the extract of H. ciliata also suggested an anxiolytic activity (Shaw et al, 2007). In holeboard test, the decoction of H. ciliata increased the number of crossing and head-dipping (exploratory activity) and decreased its latency of onset.…”

Section: Discussionmentioning

confidence: 95%

Anxiolytic - Like Properties of Hallea Ciliata in Mice

Stéphanie¹,

Gisèle²,

Clarisse³

et al. 2016

Afr J Tradit Complement Altern Med

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Background: The aim of the present study was to evaluate the anxiolytic properties of the decoction of stem bark of Hallea ciliate in mice. The decoction of Hallea ciliata is used in traditional medicine in Cameroon to treat diseases like anxiety disorders, fever, infantile convulsions and malaria. Materials and Methods: Stress induced hyperthermia, elevated plus maze, open field and hole-board tests were used. Four different doses of the decoction were administered to mice and their effects were compared to the effects of diazepam and vehicle. Phytochemical characterization of the decoction revealed the presence of alkaloids, flavonoids, tannins and saponins. Results: Administration of Hallea ciliata resulted in a significant decrease of stress induced hyperthermia in mice at the doses of 29.5, 59 and 118 mg/kg. In the elevated plus maze test, Hallea ciliata increased the number of entries and the percentages of entries and time into the open arms, and reduced the number of entries and the percentages of entries and time into the closed arms. In the hole-board test, Hallea ciliata increased the number of both head-dipping and crossing and decreased the latency to the first head-dips and rearing. The decoction of Hallea ciliata and diazepam increased locomotion in the open field test. Conclusion:The number of rearing and the mass of fecal boli produced were decreased in mice treated with decoction and diazepam. In conclusion, the results indicated that decoction of Hallea ciliata has anxiolytic-like properties in mice and could potentially be used for anxiety treatment.

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Section: Discussionmentioning

confidence: 95%

Anxiolytic - Like Properties of Hallea Ciliata in Mice

Stéphanie¹,

Gisèle²,

Clarisse³

et al. 2016

Afr J Tradit Complement Altern Med

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show abstract

“…one of the new applications of lavender oil is its use for inhalations and in alleviating anxiety and related sleep disturbances. A number of studies performed with in vitro and in vivo models reported that lavender oil has protective effects against different types of damages (1,7,12,21).…”

Section: Introductionmentioning

confidence: 99%

Studies on Antioxidant Properties before and after UV- And Γ-Irradiation of Bulgarian Lavender Essential Oil Isolated fromLavandula AngostifoliaMill

Karamalakova

Sharma

Nikolova

et al. 2013

Biotechnology & Biotechnological Equipment

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“…From the dozens of components usually found in EOs, the monoterpenes and sesquiterpenes seem to be the main responsible for central nervous system (CNS) effects (Heuberger et al, 2010). For instance, the monoterpene (R)-(-)-linalool is recognized as the sedative/ calming component of numerous traditional and commercial plant preparations and/or their EOs (Elisabetsky et al, 1995;Sugawara et al, 1998;Kuroda et al, 2005;Shaw et al, 2007;Linck et al, 2009Linck et al, , 2010Heuberger et al, …”

Section: Introductionmentioning

confidence: 99%