Aortic and Arterial Mechanics

Avril, Stéphane

doi:10.1201/b21917-6

Cited by 2 publications

(1 citation statement)

References 172 publications

(215 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Derformed (Step 10) x x Fig. 7 Displacement (along the x direction) and strain fields (E xx component) obtained by DIC on porcine sample n°1; in this particular case, the damage of the sample already reached a high value earlier after the 4th step and the strains and distortions were too high in further steps, inducing failure of the DIC and for the human aorta in the diastolic-to-systolic range which was estimated to be approximately 500 kPa [49].…”

Section: Underformedmentioning

confidence: 98%

In Vitro Measurement of Strain Localization Preceding Dissection of the Aortic Wall Subjected to Radial Tension

et al. 2020

Self Cite

View full text Add to dashboard Cite

Background Aortic dissection (AD) is a common pathology and challenging clinical problem. A better understanding of the biomechanical effects preceding its initiation is essential for predicting adverse events on a patient-specific basis. Moreover, the predictability of patient-specific biomechanics-based computational models is hampered by uncertainty about boundary conditions and material properties. Objective Predisposition of thoracic aortic aneurysms (TAA) to ADs can be related to the degradation of biomechanically important constituents in the aortic wall of TAAs. The goal of the present study is to develop a new methodology to measure strain fields in aortic tissues subjected to radial tensile loading, combining optical coherence tomography (OCT) and digital image correlation (DIC). Methods Radial tensile tests are performed on 5 samples collected from a healthy porcine descending thoracic aorta and 2 samples collected from a human ascending thoracic aortic aneurysm. At each step of the radial tensile test, the OCT technique is used to acquire images of the sample presenting a speckle pattern generated by the optical signature of the tissue. The speckle pattern is used to quantify displacement and strain fields using DIC. Stress-strain data are also measured throughout the analyzed range. Results Results show that strain commonly localizes very early during tensile tests, at the location where the crack onset occurs. Aneurysm samples even show a sharper localization than healthy porcine tissues. Conclusion This suggests the importance of extending the analysis to a larger number of human samples using our new methodology to better identify the conditions predisposing aortas to dissection.

show abstract

Section: Underformedmentioning

confidence: 98%

In Vitro Measurement of Strain Localization Preceding Dissection of the Aortic Wall Subjected to Radial Tension

et al. 2020

Self Cite

View full text Add to dashboard Cite

show abstract

In-vitro analysis of neo-sinus flow dynamics after transcatheter aortic valve replacement using particle image velocimetry technique

Xu,

Hattori,

et al. 2023

J Biorheol

View full text Add to dashboard Cite

Particle imaging velocimetry (PIV) is an effective methodology for investigating flow in the neo-sinus after transcatheter aortic valve replacement. However, understanding fluid dynamics in the lower part of the neosinus has been challenging due to limited optical access. In this study, we developed a novel PIV technique to extensively visualize the neo-sinus and to assess the potential risk of transcatheter heart valve (THV) leaflet thrombosis with the intra-annular valve. This technique involved shooting in the sinus and neo-sinus via the ventral wall of the aortic silicone model to visualize a larger region of the neo-sinus, including the lower portions (overlooking-view shooting). In the neo-sinus, stagnated flow was observed throughout the entire region in middle and late diastole. By contrast, in the native sinus, low-velocity vortical flow that inflows into the coronary artery was developed exclusively in the upper region. The present results suggest that the lower portion of the native sinus, as well as the neo-sinus, may be at high risk for leaflet thrombosis. The novel PIV technique holds promise for revealing influences of fluid dynamics on THV leaflet thrombosis with various stent flame designs.

show abstract

Aortic and Arterial Mechanics

Cited by 2 publications

References 172 publications

In Vitro Measurement of Strain Localization Preceding Dissection of the Aortic Wall Subjected to Radial Tension

In Vitro Measurement of Strain Localization Preceding Dissection of the Aortic Wall Subjected to Radial Tension

In-vitro analysis of neo-sinus flow dynamics after transcatheter aortic valve replacement using particle image velocimetry technique

Contact Info

Product

Resources

About