Aortic calcification; from innocent bystander to independent predictor; the delicate balance in biology; da aaaCapo: Editorial accompanying ‘Abdominal aortic calcification – from ancient friend to modern foe’

Larsen, Alf Inge

doi:10.1177/2047487320937130

European Journal of Preventive Cardiology

2020

DOI: 10.1177/2047487320937130

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Aortic calcification; from innocent bystander to independent predictor; the delicate balance in biology; da aaaCapo: Editorial accompanying ‘Abdominal aortic calcification – from ancient friend to modern foe’

Alf Inge Larsen

Abstract: Aortic aneurysms and the history of atherosclerosis Aneurysmal diseaseAtherosclerosis is affecting the whole cardiovascular system and might manifest itself also in a directly

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Cited by 2 publications

References 34 publications

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Comorbidity of chronic heart failure and osteoporosis: literature review

et al. 2023

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The demographic aging of the population causes an increase in the number of patients with both heart failure (HF) and osteoporosis. This is due to the strengthening of disease-preventive measures, multimorbidity, and presence of comorbid conditions such as senile asthenia. As a result, these pathological conditions can cause serious consequences such as loss of functional and social activity, disability, and high rates of hospitalization and mortality. The article considers the common risk factors of HF and osteoporosis and the leading pathophysiological mechanisms underlying these conditions. Modern ideas about the causes of bone metabolism disorders and their features in patients with HF are discussed. Data on the contribution of systemic and immune inflammation, rennin-angiotensin-aldosterone system activation in the pathogenesis, and progression of HF and osteoporosis are presented. The relationship between low bone mineral density and hemodynamic disorders in patients with HF is also shown. All this is considered in the prospect of distinguishing patients with HF as a risk group for osteoporosis and patients with decreased bone mineral density as having a high cardiovascular risk.

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Comorbidity of chronic heart failure and osteoporosis: literature review

et al. 2023

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Descending Aorta Calcinosis and Hypertension in Patients with Radiographic Axial Spondyloarthritis

Aksonova,

Kirzhner,

Smarovoz

2024

ujcvs

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This article is the result of our own clinical observations and a literature search on the development of aortic calcification and hypertension syndrome in patients with axial spondyloarthritis, as well as the clinical significance of the combination of these pathologies and management thereof. The aim. To increase the awareness of practicing doctors regarding the possible association of aortic calcification and hypertension in patients with axial spondyloarthritis, their diagnosis and possible development mechanisms. Materials and methods. For this article we described two patients with axial spondyloarthritis, calcinosis of descending aorta and high blood pressure and conducted a case-based review of related literature. Results. The article presents the results of studies, where authors tried to explain possible mechanisms of development of aortic calcification and hypertension in patients with axial spondyloarthritis. Despite the fact that the data of these studies are scattered and researchers have not yet reached a certain consensus, the available results allow us to believe that patients with axial spondyloarthritis are at increased risk for the development of aortic calcification and hypertension syndrome. Given the possible consequences of these lesions, this cohort of patients requires increased attention from clinicians of various profiles. Conclusions. Aortic calcinosis can develop in patients with axial spondyloarthritis at its various stages, and also be one of the reasons for the development of high hypertension in such patients. We consider it expedient to conduct a routine examination of the aorta in patients with radiographic axial spondyloarthritis in case of detection of hypertension in them, because this group of patients has a pathophysiological basis for the calcification of vessels of the elastic type, which is given above. This will make it possible to correctly assess the patient’s cardiovascular risks, to draw up more correct plan for their long-term management by a cardiologist in cooperation with a rheumatologist and a cardiac surgeon, as well as to choose more effective therapy for blood pressure correction.

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Aortic calcification; from innocent bystander to independent predictor; the delicate balance in biology; da aaaCapo: Editorial accompanying ‘Abdominal aortic calcification – from ancient friend to modern foe’

Abstract: Aortic aneurysms and the history of atherosclerosis Aneurysmal diseaseAtherosclerosis is affecting the whole cardiovascular system and might manifest itself also in a directly

Cited by 2 publications

References 34 publications

Comorbidity of chronic heart failure and osteoporosis: literature review

Comorbidity of chronic heart failure and osteoporosis: literature review

Descending Aorta Calcinosis and Hypertension in Patients with Radiographic Axial Spondyloarthritis

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