Aortic dissection in pregnancy: A case of Marfan's syndrome

Husebye, Kjeld O.; Wolff, Herman J.; Freidman, Louis L.

doi:10.1016/0002-8703(58)90004-8

Cited by 33 publications

(6 citation statements)

References 12 publications

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“…The early literature on pregnancy risk in women with MFS is limited to publication of single case reports or very small series . In addition, the diagnosis of MFS was not always firmly established, but presumptive, based on nonspecific skeletal features or in the setting of underlying bicuspid aortic valve, a known risk factor for aortic aneurysm and dissection.…”

Section: Discussionmentioning

confidence: 99%

Aortic Complications Associated With Pregnancy in Marfan Syndrome: The NHLBI National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC)

Roman

Pugh

Hendershot

et al. 2016

JAHA

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Section: Discussionmentioning

confidence: 99%

Aortic Complications Associated With Pregnancy in Marfan Syndrome: The NHLBI National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC)

Roman

Pugh

Hendershot

et al. 2016

JAHA

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“…23,24 Case 1 of this report was fifty-three years old at the time of diagnosis, approximately twenty years beyond the birth of her last child. The specific association between aortic dissection and pregnancy is generally found before the age of forty and most commonly occurs during the last three months of the gestational period.…”

Section: Discussionmentioning

confidence: 98%

Familial Dissecting Aortic Aneurysm in the Absence of Marfan's Syndrome with Review of the Literature: Case Report

1990

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This is a report of familial aortic dissection in a mother and son with no evidence of Marfan's syndrome in either patient. The mother, a fifty-three—year-old nurse, was evaluated initially for a four-year history of untreated hypertension and heart murmurs. Multiple cardiac complaints, including shortness of breath and chest pain on exertion, with a strong smoking history associated with an Austin-Flint murmur were noted. Subsequent laboratory studies, including electrocardiogram and cardiac catheterization, confirmed the diagnosis of dissection in the ascending aorta with free communication with an aneurysmal sac. Operative intervention included a Dacron prosthesis and porcine xenograft for aortic valve replacement. The postoperative course is unremarkable and the patient remains well after eleven years. Her twenty-eight-yearold son had a heart murmur identified on an office visit for a recurrent upper respiratory infection. Increased symptoms of shortness of breath, pulsus bisferiens, and an Austin-Flint murmur, along with findings on electrocardiogram and subsequent cardiac catheterization, confirmed the diagnosis of dissecting aortic aneurysm. The patient did not tolerate surgical intervention and a supraventricular tachycardia resulted in his death. Autopsy confirmed the extent of dissection, a 630-g heart with biventricular dilatation, hypertrophy, and dilatation of the atria; there was extensive cystic medial necrosis in the aorta. Marfan's syndrome is excluded because of the genetic predisposition to dissecting aortic aneurysm and no other findings of the Marfan's syndrome were identified. This report is to document the genetic predisposition and identification of 2 cases of congenital aortic dissection and its consequences.

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“…Moreover, there is an increased incidence of dissecting aneurysm during pregnancy (Novell, 1958; Huseby et al 1958). About 25‐50 per cent of cases of dissecting aneurysm have occurred in association with pregnancy in different series (Schnitker and Bayer, 1944).…”

Section: Comments and Discussionmentioning

confidence: 99%

A Case of the Marfan Syndrome in an Old Lady of 72 with marked Cardiovascular Involvement

Mukherjee¹

1970

Int J Clinical Practice

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Aortic dissection in pregnancy: A case of Marfan's syndrome

Cited by 33 publications

References 12 publications

Aortic Complications Associated With Pregnancy in Marfan Syndrome: The NHLBI National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC)

Aortic Complications Associated With Pregnancy in Marfan Syndrome: The NHLBI National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC)

Familial Dissecting Aortic Aneurysm in the Absence of Marfan's Syndrome with Review of the Literature: Case Report

A Case of the Marfan Syndrome in an Old Lady of 72 with marked Cardiovascular Involvement

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