Aortic Neocuspidization with Autologous Pericardium: Initial Experience of Single Center

Abstract

Background: Aortic neo-cuspidization (AVNeo) procedure has been adopted by limited centers with the publication of the mid-long term successful results. The aim of this study was to present initial experience of the AVNeo procedure of a single center. Methods: The medical records of 24 patients who underwent AVNeo with or without concomitant cardiac surgery between February 2019 and February 2021 at our tertiary hospital were scanned retrospectively. Results: The mean age of patients was aged 58.21 ± 13.14 years and 16 (66.7%) of them were men. 16 patients were operated on for aortic stenosis (66.67%). Morphology of the aortic valve was tricuspid in 21 (87.5%) and bicuspid in 3 (12.5%) of the patients. Additional cardicac surgery was performed in 13 (54.17%) patients. No patients needed reoperation for bleeding, pacemaker implantations, conversion to classical prosthetic aortic valve replacement, or infective endocarditis. Two patients died due to non-cardiac reasons. Preoperative peak and mean aortic valve pressures improved significantly at 1 st and 6 th months (

Unrecognized indication for aortic valve neocuspidization: Patient with warfarin‐induced Stevens–Johnson syndrome and toxic epidermal necrolysis

“…However, these techniques have also some limitations, such as higher pacemaker necessity rates, higher paravalvular leak rates than AVNeo procedure. 2 In addition, EOA of AVNeo procedure also had the same EOA of native aortic valve, which results with excellent hemodynamic performance. This procedure also has another significant advantage of free from anticoagulation treatment.…”

“…Stentless bioprosthetic valves and rapid deployment bioprosthetic valve technologies may also be another options for such patients. However, these techniques have also some limitations, such as higher pacemaker necessity rates, higher paravalvular leak rates than AVNeo procedure 2 . In addition, EOA of AVNeo procedure also had the same EOA of native aortic valve, which results with excellent hemodynamic performance.…”

“…We described our standard set-up of AVNeo procedure and surgical technique in our previous paper. 2 Briefly, after median sternotomy, autologous pericardium was excised and prepared. antiepileptics, and antibiotics are the drugs that most commonly cause SJS/TEN.…”

“…After sizing procedure, new cusps were trimmed with a template from the glutaraldehyde‐treated autologous pericardium. After preparation of neo‐cusps, each neo‐cusp was sewn into the appropriate region of aortic annulus, between the aortic commissures as a new aortic cusp 2,3 (Figure 3). After this procedure aortotomy was closed as usual.…”

Robotic repair of atrial septal defect with partial pulmonary venous return anomaly: Our 5 year experience

“…At this point, it would be useful to treat the pericardial patch with 0.2% glutaraldehyde solution for optimal fixation. 11 A number of procedures including a single patch or double-patch techniques have been described for this aim. Obstruction of vena cava superior or pulmonary veins are the major complications of this surgery, particularly in single patch method.…”