Aortic stenosis: A routine diagnosis with a rare cause

Abstract

A 40-year-old male patient presented with dyspnea on exertion and palpitation from 2 months ago. Physical examination revealed normal vital sign and a systolic murmur grade 3/6 in aortic area. Echocardiography revealed unicuspid aortic valve with an eccentric orifice, calcification, and aortic valve area of 0.9 cm2. This case report highlights the usefulness of three-dimensional echocardiography for the determination of number of aortic valve cusps, presence of raphe and morphology of valve.

Insights into calcific aortic valve stenosis: a comprehensive overview of the disease and advancing treatment strategies

“…These cases are generally associated with hereditary conditions or systemic inflammation, which hasten stenosis development. The unicuspid aortic valve is a rare entity that has been shown to present with AV calcifications as early as 3rd or 4th decade of life and is commonly misdiagnosed as a bicuspid aortic valvular disease 48 . Homozygous familial hypercholesterolemia is also a disease with varied clinical presentations, and even with appropriate treatment, it has been reported to present with an accelerated course of AV calcification and stenosis 49 .…”