Aorto-ostial atherosclerotic coronary artery disease—Risk factor profiles, demographic &amp; angiographic features

Verma, Sunil Kumar; Kumar, B Anil; Bahl, Vinay K.

doi:10.1016/j.ijcha.2016.05.016

Cited by 3 publications

(1 citation statement)

References 14 publications

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“…Atherosclerotic coronary artery disease (CAD) is a leading cause of global morbidity and mortality, with severe coronary ostial stenosis prevalence at 2.6% (1). The involvement of a large myocardial area can cause extensive myocardial ischemia, emphasizing the clinical significance of ostial coronary lesions (OCLs).…”

Section: Introductionmentioning

confidence: 99%

Retrospective study of treatment with a drug-coated balloon alone is beneficial for ostial coronary lesions

Zhang¹,

Ji²,

Yang³

et al. 2022

J Thorac Dis

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Background: The effects of ostial coronary lesion (OCL) treatment with a drug-coated balloon (DCB) alone remain controversial. This retrospective study assessed the effectiveness and safety with DCB only strategy for OCL and the factors associated with target lesion revascularization (TLR) in these patients. Methods:The study retrospectively included patients whom had OCLs treated with a paclitaxel-eluting DCB only strategy from 1 May 2014 to 1 May 2017. Patients were divided into in-stent restenosis (ISR) and de novo (primary) groups. And all patients came back to hospital, and underwent clinical and also angiographic follow-up.Results: Among the 44 patients with 55 OCLs, 12 (27.3%) were assigned to the ISR group and 32 (72.7%) to the de novo group. The outcomes included TLR, post-interventional lumen gain, and late lumen loss (LLL). Only 8 TLRs (7 ISR and 1 de novo) were observed after a mean follow-up of 16 months. The TLR rate in the de novo group was significantly lower than the ISR group (2.4% vs. 50%, P<0.001). The LLL was 0.07±0.63 mm. Logistic regression analysis showed that the TLR incidence was independently associated with the type of stenosis (ISR vs. de novo) after adjusting for sex [odds ratio (OR), 58.72; 95% confidence interval (CI): 4.42-779.94, P=0.002].Conclusions: Treatment with DCB alone was beneficial to patients with OCLs, particularly those with de novo lesions.

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Section: Introductionmentioning

confidence: 99%

Retrospective study of treatment with a drug-coated balloon alone is beneficial for ostial coronary lesions

Zhang¹,

Ji²,

Yang³

et al. 2022

J Thorac Dis

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Surgical coronary angioplasty of both coronary ostia after chest radiotherapy. Is it good alternative to conventional coronary bypass surgery?

Mamedov,

Rumbinaitė,

Karčiauskas

et al. 2023

Perfusion

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Introduction Isolated coronary ostial stenosis of both ostia is a rare, potentially life-threatening condition, occurring in 0.1%–0.2% of patients undergoing coronary angiography. Case report We present a case of a 69-year-old woman with a past medical history of breast cancer, who had been treated with radiotherapy, which most likely caused significant stenosis of both coronary ostia and likely accelerated aortic stenosis. Surgical angioplasty with autopericardium patch reconstruction of the left main coronary artery and right coronary arteries due to proximal stenotic disease was performed instead of venous or arterial bypasses with concomitant aortic valve replacement. The postoperative course was uneventful. There were no cardiovascular events 5 years after operation, and the patient remained free of any symptoms. Conclusions Surgical coronary angioplasty offers an alternative to conventional coronary artery bypass grafting in isolated coronary ostial lesions and is advantageous in restoring more physiological myocardial perfusion, especially in those cases when conduits are suspected to be fibrotic, scarred or stenosed after radiation therapy or if there is the need to preserve conduits for future myocardial revascularisation in young patients.

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Male Patients with Takayasu Arteritis and Coronary Artery Involvement are Prone to Have Serious Coronary Stenosis and High Mortality

Zhao

2022

CVP

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Background: Takayasu arteritis (TAK) is a rare autoimmune vasculitis that predominantly affects the aorta and its major branches, including the coronary arteries. Limited information is available regarding sex-specific differences in coronary artery involvement among TAK patients. Objective: To assess the differences in coronary angiographic findings and the long-term outcomes between male and female TAK patients having coronary artery involvement. Methods: This retrospective cohort study included 87 TAK patients, grouped by sex, who underwent coronary angiography. General characteristics, clinical features, coronary angiographic findings, and therapeutic strategies were obtained from medical records. Major Adverse Cardiac Events (MACE), including death from any cause; myocardial infarction; repeated coronary artery revascularization; and rehospitalization due to unstable or progressive angina, or heart failure occurring during follow-up, were also recorded. Results: A total of 207 coronary lesions with stenosis were found in 87 TAK patients. The prevalence of ostial coronary lesions was lower in men than in women (9.1 vs. 23.9%, p=0.031). We observed less moderate stenosis (6.8 vs 22.7%, p=0.018) and more severe stenosis or occlusion (70.5 vs 46.0%, p=0.004) in the coronary lesions of male TAK patients. During the up to 7-year follow-up, death from any cause was greater in men than in women (21.4 vs. 1.5%, p=0.003); no other significant differences in MACE occurrence were observed between sexes. Conclusions: Among TAK patients with coronary artery involvement, males tend to have more severe coronary stenosis and a higher risk for long-term mortality than females.

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Aorto-ostial atherosclerotic coronary artery disease—Risk factor profiles, demographic & angiographic features

Cited by 3 publications

References 14 publications

Retrospective study of treatment with a drug-coated balloon alone is beneficial for ostial coronary lesions

Retrospective study of treatment with a drug-coated balloon alone is beneficial for ostial coronary lesions

Surgical coronary angioplasty of both coronary ostia after chest radiotherapy. Is it good alternative to conventional coronary bypass surgery?

Male Patients with Takayasu Arteritis and Coronary Artery Involvement are Prone to Have Serious Coronary Stenosis and High Mortality

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