Aortoiliac Occlusion Associated with the Lupus Anticoagulant

Setoguchi, Motoko; Fujishima, Y; Abe, Isao; Kobayashi, Kazuo; Fujishima, Masatoshi

doi:10.1177/000331979704800410

Cited by 6 publications

(1 citation statement)

References 9 publications

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“…It should be borne in mind that lower‐limb claudication may also occur consequently to occlusion of the abdominal aorta itself, as exemplified by the cases reported by Drew et al , 20 Ter Borg et al , 21 and Hohlfeld et al ., 22 or the aorto‐iliac bifurcation 23 . McGee et al .…”

Section: Occlusions Of Aorta/aortic Bifurcationmentioning

confidence: 99%

Peripheral Vascular Occlusions Leading to Gangrene and Amputations in Antiphospholipid Antibody Positive Patients

Asherson

Cervera

Shoenfeld

2007

Annals of the New York Academy of Sciences

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Twenty-one cases from several medical centers (Brazil, Italy, Serbia, South Africa, Israel, and the United Kingdom) with severe peripheral vascular disease progressing to amputations of limbs/digits, all of whom tested positive for antiphospholipid antibodies, are documented. The patients were suffering from either systemic lupus erythematosus, discoid LE, "primary" antiphospholipid syndrome (PAPS), "lupus-like" disease, undifferentiated connective tissue disease. A high frequency of livedo reticularis preceding the arterial occlusions in our series of patients who subsequently progressed to ischemic necrosis and amputation of limbs/digits was noted. Five of the 10 patients, in whom histopathological studies had been performed, demonstrated the typical vasculopathy seen with the antiphospholipid syndrome ("APS vasculopathy"). Complicating vasculitis was present in seven of the patients. Five of the patients developed severe peripheral vascular disease during the course of the catastrophic antiphospholipid (Asherson's) syndrome.

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Section: Occlusions Of Aorta/aortic Bifurcationmentioning

confidence: 99%