“…Recently, studies have shown that both systemic inflammation during infection and systemic inflammation resulting from untreated medical conditions (e.g., gastrointestinal illnesses such as Crohn's disease or persistent diarrhea) are associated with low levels of important growth factors (e.g., insulin‐like growth factor [IGF‐1]) and poor responsiveness of growth plates, thus impairing linear growth (Bhutta et al, ; De Boer & Denson, ; De Boer et al, ; MacRae, Farquharson, & Ahmed, ). The South African coloured sample experienced malnutrition, lack of proper medical care, and high exposure to infectious diseases and illnesses as a result of discrimination and segregation stemming from the apartheid regime (1948‐1994) (Das‐Munshi et al, ; Harris et al, ; Pfeiffer, Heinrich, Beresheim, & Alblas, ; Turton & Chalmers, ; Wisner, ). In particular, death certificates associated with individuals represented in the Kirsten Skeletal Collection list gastrointestinal illnesses as one of the untreated conditions which affected morbidity in the sample (Pfeiffer et al, ).…”