Aphrodisiac property of Trichopus zeylanicus extract in male mice

Subramoniam, A.; Madhavachandran, V.; Rajasekharan, S.; Pushpangadan, P.

doi:10.1016/s0378-8741(97)00040-8

Cited by 62 publications

(41 citation statements)

References 2 publications

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“…The outcome of this study indicates that the effects of DM in improving sexual behavior are sustained even after withdrawal of the treatment. The enhancement of libido may be due to an increase in the anterior pituitary hormone and serum testosterone levels, which in turn stimulates sexual behavior [18,19]. Further studies will be required to elucidate the mechanism underlying the association between sexual behavior and androgens.…”

Section: Discussionmentioning

confidence: 99%

Effect of Aqueous Extract of <i>Dendropanax morbifera</i> Leaf on Sexual Behavior in Male Rats

Jung¹,

Oh²,

Choi³

et al. 2017

JFNR

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Sexual function in an important of the quality of life and subjective well-being in humans. Successful treatment of sexual dysfunction may improve not only sexual relationships, but also overall quality of life. The objective of this study was to determine the effects of Dendropanax morbifera (DM) Lev. leaf extracts on sexual behavior and testosterone levels in male rats. Three different doses of DM (50, 100, and 200 mg/kg/day) were administered orally for 28 days. On day 28 (final day of the sample treatment period) and day 42 (after 2 weeks of sample withdrawal period following 28 days of sample treatment), serum testosterone levels and sexual behavior of rats were determined, including mount frequency (MF), intromission frequency, mount latency (ML, the time from introduction of the female to the male to the first mount), intromission latency (IL), and post-ejaculatory interval (PEI). ML significantly reduced, whereas MF increased in the DM group. The DM group also had a reduced PEI. The oral administration of DM significantly increased serum testosterone levels compared with those in the control group. The results of this study demonstrate that an aqueous extract of DM represents a useful natural resource for the management of sexual function.

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Section: Discussionmentioning

confidence: 99%

Effect of Aqueous Extract of <i>Dendropanax morbifera</i> Leaf on Sexual Behavior in Male Rats

Jung¹,

Oh²,

Choi³

et al. 2017

JFNR

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“…The experimental extract and the pure compound were introduced 15 minutes after acclimatization period. The activity of male rat in each group was recorded individually for 60 minutes, after 30 minutes of drug administration [17][18][19][20]. To determine the aphrodisiac activity of the extracts, several parameters were observed.…”

Section: Methodsmentioning

confidence: 99%

Study on Aphrodisiac Activity of Olea Dioica Roxb. Bark, Leaf Extracts, and Its Pure Compound Using Wistar Albino Rats

Ashwathanarayana

Naika

2017

Asian J Pharm Clin Res

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Objectives: We aimed to assess the effects of O. dioica Roxb. leaf and bark extract and its isolated constituent benzeneethanol, 4-hydroxy-on aphrodisiac activity in rats using different standard aphrodisiac parameters. Methods:To determine the aphrodisiac activity several parameters were observed. These include measuring and observing the mount frequency (MF), mount latency (ML), intromission frequency (IF), intromission latency (IL), anogenital sniffing (AS), and genital grooming (GG). Results:The aphrodisiac activity of O. dioica Roxb. leaf and bark extracts and its pure compound were studied on Wistar albino rats at different dosages. The parameters observed during the study were MF, ML, IF, IL, AS, and GG. The results revealed that the crude extracts showed dosedependent activity in all the concentration, in that, ethanolic leaf extract showed excellent activity compared to ethanolic bark extract and pure compound benzene ethanol 4-hydroxy. Conclusion:Results showed the excellent aphrodisiac activity of O. dioica Roxb. leaf and bark ethanolic extracts. However, the major compound benzeneethanol, 4-hydroxy-was not responsible for the aphrodisiac activity, may be the minor compounds even though in minor concentration in the extract influence the sexual activity in tested animals.

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“…[9][10][11] A mount is operationally defined as the male assuming the copulatory position but failing to achieve intromission. [12,13] …”

Section: Test Of Libidomentioning

confidence: 99%

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Malviya¹

2017

IJGP

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Male sexual dysfunctions manifested by disorders of sexual desire (hypoactive and hyperactive), disorders of erection (erectile dysfunction), disorders of ejaculation (premature, absent/delayed and painful ejaculation, disorders of orgasm, and failure of detumescence). Conventional medicine is the knowledge, skills, and practice of holistic health care and recognized and accepted for its role in the maintenance of health and the treatment of diseases. It is based on indigenous theories, beliefs, and experiences that are handed down from generation to generation. Conventional medicine is practiced in many countries; it has always been part of the cultural and religious life of Indian people. Herbal treatments are the most popular forms of traditional medicine and are highly lucrative in the international marketplace. Today, more than 80% population of the developing countries depends on plants for their medical needs. Therefore, the increasing search for medicinal plants used in the treatment and management of male sexual dysfunction has necessitated. There are many herbal drugs that have been used for the treatment and management of male sexual dysfunction with varying degrees of success such as Tribulus terrestris, Withania somnifera, Eurycoma longifolia, Ginkgo biloba, and Myristica fragrans. Based on historical experience in traditional system of medicines, herbal medicinal plants are recommended for the treatment and management of male sexual dysfunction, and few of them have been scientifically validated. Recently, preclinical screening models including use of small animals such as rats and mice have been developed for better assessment of the pharmacological potential of medicinal plants against male sexual dysfunction. The present article has summarized the preclinical screening parameters with their significance including mating performance analysis, changes in reproductive organs index, reproductive hormonal estimations, sperm analysis, and histoarchitecture investigations.

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Aphrodisiac property of Trichopus zeylanicus extract in male mice

Cited by 62 publications

References 2 publications

Effect of Aqueous Extract of <i>Dendropanax morbifera</i> Leaf on Sexual Behavior in Male Rats

Effect of Aqueous Extract of <i>Dendropanax morbifera</i> Leaf on Sexual Behavior in Male Rats

Study on Aphrodisiac Activity of Olea Dioica Roxb. Bark, Leaf Extracts, and Its Pure Compound Using Wistar Albino Rats

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