Apical aortic blood pump preclinical assessment for long‐term use: Durability test and stator topology to reduce wear in the bearing system

Silva, Bruno Utiyama da; Fonseca, Jeison; Leal, Edir Branzoni; Cardoso, José Roberto; Biscegli, José Francisco; Andrade, Aron José Pazin de

doi:10.1111/aor.13587

Cited by 8 publications

(8 citation statements)

References 8 publications

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“…The AABP, designed as a centrifugal blood pump with ceramic bearings, is intended for long-term circulatory assistance as an implantable LVAD. The AABP is directly affixed to the left ventricular apex and connected to the aorta through an outlet cannula [33]. The actuator for the AABP is a brushless direct current (BLDC) motor driven by a 50/4 EC-S electronic system (Maxon, Sachseln, Switzerland) configured using ESCON Studio software (V.18, Maxon, Sachseln, Switzerland).…”

Section: Hybrid Cardiovascular Simulator (Hcs) Testsmentioning

confidence: 99%

Embedded Cyber-physical System for Physiological Control of Ventricular Assist Devices

Santos,

Leao,

Barboza

et al. 2024

Preprint

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Left Ventricular Assist Devices (LVADs) serve as both a bridge to transplantation and a destination therapy for managing congestive heart failure (CHF). However, the existing control strategy's inability to automatically adapt to hemodynamic changes can significantly impact patient survival rates and quality of life. Researchers have proposed various approaches to achieve Physiological Control over LVADs (PC-LVAD). Despite promising results, implementing these strategies on computers faces limitations due to substantial differences in controller characteristics between computers and embedded systems. An embedded cyber-physical system (CPS) was proposed to address this challenge, integrating real-time data processing, reconfigurable architecture, and communication protocols based on Health 4.0 concepts. To evaluate this embedded CPS, a multi-objective PC-LVAD was utilized in a hybrid cardiovascular simulator with an implanted LVAD, testing symmetry between the original proposal of the PC-LVAD and the version running on the embedded CPS. The embedded CPS demonstrated comparable results to the control executed on a computer, maintaining mean arterial pressure and cardiac output at physiological levels, even amid variations in ejection fraction. Furthermore, the pump's rotational speed was dynamically adjusted based on simulated clinical conditions, and no aortic reflux to the ventricle occurred through the LVAD during testing. These outcomes affirm the embedded CPS's satisfactory control performance. However, additional testing is imperative to validate its enhanced physiological strategies in embedded CPS during in vivo experiments.

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Section: Hybrid Cardiovascular Simulator (Hcs) Testsmentioning

confidence: 99%

Embedded Cyber-physical System for Physiological Control of Ventricular Assist Devices

Santos,

Leao,

Barboza

et al. 2024

Preprint

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“…The original purpose of the AABP was to provide circulatory assistance as a BTT strategy [ 13 ] . However, durability tests were favorable to an eventual application of the device as a long-term circulatory assistance or for destination therapy [ 14 ] .…”

Section: New Centrifugal Pumpsmentioning

confidence: 99%

Ventricular Assist Device Research and Development in Brazil: A Long and Promising Relationship Between Medicine and Engineering

Karigyo,

Fonseca,

Boscarato

et al. 2023

Braz J Cardiovasc Surg

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“…The typical bearing wear rate was obtained to be less than 1.46 μm/yr. Recently, Da Silva et al [123] studied the long-term use of the apical aortic blood pump by wear reduction of the bearing components. Their durability test indicates that wear in the lower bearing pivot causes device failure.…”

Section: Research Advances On the Bio-tribology Of Cardiovascular Devicesmentioning

confidence: 99%

A review of the bio-tribology of medical devices

Zhang

2021

Friction

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Numerous medical devices have been applied for the treatment or alleviation of various diseases. Tribological issues widely exist in those medical devices and play vital roles in determining their performance and service life. In this review, the bio-tribological issues involved in commonly used medical devices are identified, including artificial joints, fracture fixation devices, skin-related devices, dental restoration devices, cardiovascular devices, and surgical instruments. The current understanding of the bio-tribological behavior and mechanism involved in those devices is summarized. Recent advances in the improvement of tribological properties are examined. Challenges and future developments for the prospective of bio-tribological performance are highlighted.

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Apical aortic blood pump preclinical assessment for long‐term use: Durability test and stator topology to reduce wear in the bearing system

Cited by 8 publications

References 8 publications

Embedded Cyber-physical System for Physiological Control of Ventricular Assist Devices

Embedded Cyber-physical System for Physiological Control of Ventricular Assist Devices

Ventricular Assist Device Research and Development in Brazil: A Long and Promising Relationship Between Medicine and Engineering

A review of the bio-tribology of medical devices

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